BIOSYNTHESIS OF POLYPHENOLS IN SALVIA SPECIES

KA Sheikh; M Maqsood; MU Rehman; S Sarwar; AA Qayyum; Q Ali

doi:10.54112/bcsrj.v2021i1.64

Authors

KA Sheikh Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore Pakistan
M Maqsood Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore Pakistan
MU Rehman Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore Pakistan
S Sarwar Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore Pakistan
AA Qayyum Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore Pakistan
Q Ali Institute of Molecular Biology & Biotechnology, University of Lahore, Lahore, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2021i1.64

Keywords:

salvia, caffeic acid, cytotoxic, cancer, anti-inflammatory

Abstract

Chinese Salvia Species also called as “sages” are known as full of polyphenols that are rich source of natural antioxidants which are used to decrease levels of free radicals. Caffeic acid is an antioxidant present in Salvia as a secondary metabolite in plant metabolism. Many species of this plant are used in the treatment of degenerative disorders like cancer due to its anti-inflammatory, anti-oxygenation, anti-tumor and cytotoxic properties. Because of these specific properties of salvia species it is used in food, cosmetics and pharmaceutical industries.

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References

Chiva-Blanch, G., and Visioli, F. (2012). Polyphenols and health: Moving beyond antioxidants. Journal of Berry Research 2, 63-71.

D’Amelia, V., Ruggiero, A., Tranchida-Lombardo, V., Leone, A., Tucci, M., and Docimo, T. (2017). Biosynthesis of salvia specialized metabolites and biotechnological approaches to increase their production. In "Salvia Biotechnology", pp. 241-270. Springer.

Grzegorczyk-Karolak, I., Kuźma, Ł., Skała, E., and Kiss, A. K. (2018). Hairy root cultures of Salvia viridis L. for production of polyphenolic compounds. Industrial crops and products 117, 235-244.

Hernández-Morales, L., Espinoza-Gómez, H., Flores-López, L. Z., Sotelo-Barrera, E. L., Núñez-Rivera, A., Cadena-Nava, R. D., Alonso-Núñez, G., and Espinoza, K. A. (2019). Study of the green synthesis of silver nanoparticles using a natural extract of dark or white Salvia hispanica L. seeds and their antibacterial application. Applied Surface Science 489, 952-961.

Li, C., Li, D., Li, J., Shao, F., and Lu, S. (2017). Characterization of the polyphenol oxidase gene family reveals a novel microRNA involved in posttranscriptional regulation of PPOs in Salvia miltiorrhiza. Scientific reports 7, 1-15.

Lopresti, A. L. J. D. i. R. (2017). Salvia (sage): a review of its potential cognitive-enhancing and protective effects. 17, 53-64.

Ma, X.-H., Ma, Y., Tang, J.-F., He, Y.-L., Liu, Y.-C., Ma, X.-J., Shen, Y., Cui, G.-H., Lin, H.-X., and Rong, Q.-X. (2015). The biosynthetic pathways of tanshinones and phenolic acids in Salvia miltiorrhiza. Molecules 20, 16235-16254.

Min-hui, L., Jian-min, C., Yong, P., and Pei-gen, X. (2008). Distribution of phenolic acids in Chinese Salvia plants. World Science and Technology 10, 46-52.

Oueslati, M. H., Ben Tahar, L., and Harrath, A. H. (2020). Synthesis of ultra-small gold nanoparticles by polyphenol extracted from Salvia officinalis and efficiency for catalytic reduction of p-nitrophenol and methylene blue. Green Chemistry Letters and Reviews 13, 18-26.

Scalbert, A., Johnson, I. T., and Saltmarsh, M. (2005). Polyphenols: antioxidants and beyond. The American journal of clinical nutrition 81, 215S-217S.

Sharopov, F., Valiev, A., Sobeh, M., Arnold, E., and Winka, M. J. P. C. J. (2018). Bioactivity of three Salvia species in relation to their total phenolic and flavonoid contents. 52, 596-600.

Shi, M., Huang, F., Deng, C., Wang, Y., and Kai, G. (2019). Bioactivities, biosynthesis and biotechnological production of phenolic acids in Salvia miltiorrhiza. Critical reviews in food science and nutrition 59, 953-964.

Wang, J., Xu, J., Gong, X., Yang, M., Zhang, C., and Li, M. (2019a). Biosynthesis, chemistry, and pharmacology of polyphenols from Chinese Salvia species: A review. Molecules 24, 155.

Wang, J., Xu, J., Gong, X., Yang, M., Zhang, C., and Li, M. (2019b). Biosynthesis, Chemistry, and Pharmacology of Polyphenols from Chinese Salvia Species: A Review. Molecules 24.

Wang, J., Xu, J., Gong, X., Yang, M., Zhang, C., and Li, M. J. M. (2019c). Biosynthesis, chemistry, and pharmacology of polyphenols from Chinese Salvia species: A review. 24, 155.

Wang, L., Ma, R., Liu, C., Liu, H., Zhu, R., Guo, S., Tang, M., Li, Y., Niu, J., Fu, M., Gao, S., and Zhang, D. (2017). Salvia miltiorrhiza: A Potential Red Light to the Development of Cardiovascular Diseases. Curr Pharm Des 23, 1077-1097.