PERCEPTION REGARDING SELF-MEDICATION OF ANTIBIOTICS IN GENERAL PUBLIC SECTOR UNIVERSITY OF SOUTHERN PUNJAB: A COMPARISON BETWEEN MEDICAL AND NON-MEDICAL STUDENTS

S Khalid; Q Ali; MM Hafeez; A Malik

doi:10.54112/bcsrj.v2021i1.51

Authors

S Khalid Institute of Molecular Biology & Biotechnology, University of Lahore, Lahore, Pakistan
Q Ali
MM Hafeez Institute of Molecular Biology & Biotechnology, University of Lahore, Lahore, Pakistan
A Malik Institute of Molecular Biology & Biotechnology, University of Lahore, Lahore, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2021i1.51

Keywords:

self-medication, antibiotics, pharmacology, drugs, Augmentin, Amoxicillin

Abstract

Self-medication with antibiotics is a most rapidly emerging problem especially in developing countries like Pakistan. Antibiotics are easily accessible to the general public without consulting any practitioner even without prescriptions. So there are many risks linked to the inappropriate use of antibiotics. The main aim of this study was to assess the wrong practice of self-medication in public sector universities of southern Punjab. The current study also compares the self-medication practices in various departments of universities. A validated questionnaire was used to collect data. Descriptive statistics were used to analyze the data and inferential statistics (chi-square test). The study was included data from 900 students including both males and females from various departments. Among 900 students, 450 students of medical while 450 were non-medical students. Frequency of self-medication was found to 57 %. The antibiotics more frequently use for self-medication were Augmentin (37 %), Amoxicillin (23 %). Fever and cough were the most frequent indication for the use of self-medicated antibiotics. Because of their sufficient knowledge of pharmacology, most students were self-medicated (40%). Academic knowledge is the principal source of antibiotic information (60%). Just (39%) of the students thought that self-medication is part of the self-core, 31% of the students perceived that the availability of non-prescription drugs could prevent the growing trend of self-medication with antibiotics. 30% of students perceived that antibiotics were aware of the harms of self-medication or informed about them. Based on this study, it can be concluded that a high proportion of medical students and non-medical students use antibiotics without medical prescription and such practices are more common in the general public sector.

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References

Al-Azzam, S. I., Al-Husein, B. A., Alzoubi, F., and Masadeh, M. M. (2007). Self-medication with antibiotics in Jordanian population. International journal of occupational medicine and environmental health 20, 373.

Awad, A., Eltayeb, I., Matowe, L., and Thalib, L. (2005). Self-medication with antibiotics and antimalarials in the community of Khartoum State, Sudan. J Pharm Pharm Sci 8, 326-331.

Bronzwaer, S. (2002). European Antimicrobial Resistance Surveillance System. A European study on the relationship between antimicrobial use and antimicrobial resistance. Emerg Infect Dis 8, 278-282.

Bryce, A., Hay, A. D., Lane, I. F., Thornton, H. V., Wootton, M., and Costelloe, C. (2016). Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: systematic review and meta-analysis. bmj 352, i939.

Davey, P., Brown, E., Fenelon, L., Finch, R., Gould, I., Holmes, A., Ramsay, C., Taylor, E., Wiffen, P., and Wilcox, M. (2006). Systematic review of antimicrobial drug prescribing in hospitals. Emerging infectious diseases 12, 211.

Exner, M., Bhattacharya, S., Christiansen, B., Gebel, J., Goroncy-Bermes, P., Hartemann, P., Heeg, P., Ilschner, C., Kramer, A., and Larson, E. (2017). Antibiotic resistance: What is so special about multidrug-resistant Gram-negative bacteria? GMS hygiene and infection control 12.

Gonzales, R., Bartlett, J. G., Besser, R. E., Cooper, R. J., Hickner, J. M., Hoffman, J. R., and Sande, M. A. (2001). Principles of appropriate antibiotic use for treatment of acute respiratory tract infections in adults: background, specific aims, and methods. Annals of internal medicine 134, 479-486.

Goossens, H., Ferech, M., Vander Stichele, R., Elseviers, M., and Group, E. P. (2005). Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. The Lancet 365, 579-587.

Grigoryan, L., Burgerhof, J. G., Haaijer-Ruskamp, F. M., Degener, J. E., Deschepper, R., Monnet, D. L., Di Matteo, A., Scicluna, E. A., Bara, A.-C., and Lundborg, C. S. (2007). Is self-medication with antibiotics in Europe driven by prescribed use? Journal of Antimicrobial Chemotherapy 59, 152-156.

Grigoryan, L., Haaijer-Ruskamp, F. M., Burgerhof, J. G., Mechtler, R., Deschepper, R., Tambic-Andrasevic, A., Andrajati, R., Monnet, D. L., Cunney, R., and Di Matteo, A. (2006). Self-medication with antimicrobial drugs in Europe. Emerging infectious diseases 12, 452.

Guillemot, D., Carbon, C., Balkau, B., Geslin, P., Lecoeur, H., Vauzelle-Kervroëdan, F., Bouvenot, G., and Eschwége, E. (1998). Low dosage and long treatment duration of β-lactam: risk factors for carriage of penicillin-resistant Streptococcus pneumoniae. Jama 279, 365-370.

Harbarth, S., Albrich, W., and Brun-Buisson, C. (2002). Outpatient antibiotic use and prevalence of antibiotic-resistant pneumococci in France and Germany: a sociocultural perspective. Emerging infectious diseases 8, 1460.

Holmes, A. H., Moore, L. S., Sundsfjord, A., Steinbakk, M., Regmi, S., Karkey, A., Guerin, P. J., and Piddock, L. J. (2016). Understanding the mechanisms and drivers of antimicrobial resistance. The Lancet 387, 176-187.

Huttner, B., Goossens, H., Verheij, T., and Harbarth, S. (2010). Characteristics and outcomes of public campaigns aimed at improving the use of antibiotics in outpatients in high-income countries. The Lancet infectious diseases 10, 17-31.

Johnston, A. (1998). Use of antimicrobial drugs in veterinary practice. Bmj 317, 665-667.

Laxminarayan, R., Duse, A., Wattal, C., Zaidi, A. K., Wertheim, H. F., Sumpradit, N., Vlieghe, E., Hara, G. L., Gould, I. M., and Goossens, H. (2013). Antibiotic resistance—the need for global solutions. The Lancet infectious diseases 13, 1057-1098.

Lipsitch, M., and Samore, M. H. (2002). Antimicrobial use and antimicrobial resistance: a population perspective. Emerging infectious diseases 8, 347.

Llor, C., and Bjerrum, L. (2014). Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem. Therapeutic advances in drug safety 5, 229-241.

Marston, H. D., Dixon, D. M., Knisely, J. M., Palmore, T. N., and Fauci, A. S. (2016). Antimicrobial resistance. Jama 316, 1193-1204.

Morgan, D. J., Okeke, I. N., Laxminarayan, R., Perencevich, E. N., and Weisenberg, S. (2011). Non-prescription antimicrobial use worldwide: a systematic review. The Lancet infectious diseases 11, 692-701.

Napolitano, F., Izzo, M. T., Di Giuseppe, G., and Angelillo, I. F. (2013). Public knowledge, attitudes, and experience regarding the use of antibiotics in Italy. PloS one 8, e84177.

Okeke, I. N., Laxminarayan, R., Bhutta, Z. A., Duse, A. G., Jenkins, P., O'Brien, T. F., Pablos-Mendez, A., and Klugman, K. P. (2005). Antimicrobial resistance in developing countries. Part I: recent trends and current status. The Lancet infectious diseases 5, 481-493.

Okumura, J., Wakai, S., and Umenai, T. (2002). Drug utilisation and self-medication in rural communities in Vietnam. Social science & medicine 54, 1875-1886.

Parimi, N., Pereira, L. M. P., and Prabhakar, P. (2004). Caregivers' practices, knowledge and beliefs of antibiotics in paediatric upper respiratorytract infections in Trinidad and Tobago: a cross-sectional study. BMC family practice 5, 28.

Picazo, J. J., Pérez-Cecilia, E., and Herreras, A. (2003). Respiratory infections outside the hospital. DIRA study. Enfermedades infecciosas y microbiologia clinica 21, 410-416.

Richman, P. B., Garra, G., Eskin, B., Nashed, A. H., and Cody, R. (2001). Oral antibiotic use without consulting a physician: a survey of ED patients. The American journal of emergency medicine 19, 57-60.

Ruiz, M. E. (2010). Risks of self-medication practices. Current drug safety 5, 315-323.

Samaranayake, L., and Johnson, N. (1999). Guidelines for the use of antimicrobial agents to minimise development of resistance: FDI Commission. International dental journal 49, 189-195.

Silbergeld, E. K., Graham, J., and Price, L. B. (2008). Industrial food animal production, antimicrobial resistance, and human health. Annu. Rev. Public Health 29, 151-169.

Smith, R. D., Coast, J., Millar, M. R., Wilton, P., and Karcher, A.-M. (2001). Interventions against antimicrobial resistance: A review of the literature and exploration of modelling cost-effectiveness. In "Geneva: Global Forum for Health Research". Citeseer.

Stratchounski, L., Andreeva, I., Ratchina, S., Galkin, D., Petrotchenkova, N., Demin, A., Kuzin, V., Kusnetsova, S., Likhatcheva, R., and Nedogoda, S. (2003). The inventory of antibiotics in Russian home medicine cabinets. Clinical infectious diseases 37, 498-505.

Van Boeckel, T. P., Gandra, S., Ashok, A., Caudron, Q., Grenfell, B. T., Levin, S. A., and Laxminarayan, R. (2014). Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. The Lancet infectious diseases 14, 742-750.

WHO (2001). "WHO global strategy for containment of antimicrobial resistance." World Health Organization.