PREVALENCE OF HEPATITIS B IN LOCAL AREA OF DISTRICT SIALKOT, PAKISTAN

S MUZAMMAL; S ASHRAF; T NASIR; S ZAINAB; M ATIF; F IRSHAD; K AMJAD

doi:10.54112/bcsrj.v2024i1.864

Authors

S MUZAMMAL Department of Zoology, University of Sialkot, Pakistan
S ASHRAF Department of Zoology, University of Sialkot, Pakistan
T NASIR Department of Zoology, Lahore College for Women University Lahore, Pakistan
S ZAINAB Department of Zoology, University of Sialkot, Pakistan
M ATIF Department of Zoology University of Narowal, Pakistan
F IRSHAD Department of Zoology, University of Sialkot, Pakistan
K AMJAD Department of Zoology, University of Sialkot, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2024i1.864

Keywords:

Hepatitis B, Immunochromatography, Incidence, Liver Diseases, Pakistan, Sialkot

Abstract

Hepatitis B virus (HBV), a small encapsulated DNA virus, predominantly infects hepatocytes, causing acute and chronic liver damage. Objective: This study aimed to assess the incidence of HBV among the population of the local area of district Sialkot. Methods: A hospital-based study was conducted at Tehsil Headquarters Hospital Daska between January 2022 and May 2022. Sixty participants were registered for the study, including males and females aged 7 to 68. Data collection was performed using a standardised questionnaire. Each participant provided 5 ml of blood for an immunochromatography test. Descriptive statistics were used to analyse the data. Results: Out of the 60 participants, 20 tested reactive for HBV, with 18 males and 2 females. Most of the reactive participants were males aged between 20 and 40, and most were married. Conclusion: The findings indicate a significant incidence of HBV among males, particularly those aged 20-40 years in the district of Sialkot. These results can inform public health initiatives to prevent HBV and promote precautionary measures.

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References

Shen C, Jiang X, Li M, Luo Y. Hepatitis virus and hepatocellular carcinoma: recent advances. Cancers. 2023;15(2):533.

Li H, Yan L, Shi Y, Lv D, Shang J, Bai L, et al. Hepatitis B virus infection: overview. Hepatitis B Virus Infection: Molecular Virology to Antiviral Drugs. 2020:1-16.

Campbell C, Wang T, McNaughton AL, Barnes E, Matthews PC. Risk factors for the development of hepatocellular carcinoma (HCC) in chronic hepatitis B virus (HBV) infection: a systematic review and meta‐analysis. Journal of viral hepatitis. 2021;28(3):493-507.

Lee HM, Banini BA. Updates on chronic HBV: current challenges and future goals. Current treatment options in gastroenterology. 2019;17:271-91.

Chen T, Yang Z, Choudhury AK, Al Mahtab M, Li J, Chen Y, et al. Complications constitute a major risk factor for mortality in hepatitis B virus-related acute-on-chronic liver failure patients: a multi-national study from the Asia–Pacific region. Hepatology international. 2019;13:695-705.

Armencia A, Saveanu I, Budala D, Bolat M, Hurjui L, Gradinaru I, et al. KNOWLEDGE AND ATTITUDES REGARDING THE TRANSMISSION OF BLOOD INFECTION AMONG GENERAL AND DENTAL STUDENTS IN IASI, ROMANIA. Romanian Journal of Medical and Dental Education. 2019;8(12).

Sheikh AN, Siddiquee B, Chahande J. Hepatitis B and C infection among dentists–Risk, prevention, and management. Journal of Advances in Dental Practice and Research. 2022;1(1):31-6.

Obeagu E, Obeagu G, Nwosu D. Hepatitis B and Hepatitis C viral infection: A Review. Int J Curr Res Chem Pharm Sci. 2016;3(11):10-21.

Trickey A, May MT, Davies C, Qureshi H, Hamid S, Mahmood H, et al. Importance and contribution of community, social, and healthcare risk factors for hepatitis C infection in Pakistan. The American journal of tropical medicine and hygiene. 2017;97(6):1920.

Pandyarajan V, Govalan R, Yang JD. Risk factors and biomarkers for chronic hepatitis B associated hepatocellular carcinoma. International journal of molecular sciences. 2021;22(2):479.

Singal AG, Llovet JM, Yarchoan M, Mehta N, Heimbach JK, Dawson LA, et al. AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma. Hepatology. 2023;78(6):1922-65.

Bilal W, Qamar K, Abbas S, Siddiqui A, Essar MY. Infectious diseases surveillance in Pakistan: challenges, efforts, and recommendations. Annals of Medicine and Surgery. 2022;78.

Howell J, Pedrana A, Schroeder SE, Scott N, Aufegger L, Atun R, et al. A global investment framework for the elimination of hepatitis B. Journal of hepatology. 2021;74(3):535-49.

Khan N, Cailhol J. Are migration routes disease transmission routes? Understanding Hepatitis and HIV transmission amongst undocumented Pakistani migrants and asylum seekers in a Parisian suburb. Anthropology & Medicine. 2020;27(4):395-411.

Wang SH, Chen PJ, Yeh SH. Gender disparity in chronic hepatitis B: mechanisms of sex hormones. Journal of gastroenterology and hepatology. 2015;30(8):1237-45.

Khatoon R, Jahan N. Evaluation of seroprevalence of Hepatitis B virus infection among patients attending a hospital of semi-urban North India using rapid immunoassay test. Nigerian Postgraduate Medical Journal. 2016;23(4):209-14.