PREVALENCE OF H. PYLORI INFECTION IN PATIENTS PRESENTING WITH PERFORATED DUODENAL ULCER

Authors

  • M NAEEM Mardan Medical Complex Mardan, Pakistan
  • S AHMAD Department of Gastroenterology, DHQ Hospital Mardan, Pakistan
  • H ULLAH Qazi Hussain Ahmad Medical Complex, Nowshera, Pakistan
  • . MUJAHID Lady Reading Hospital, Peshawar, Pakistan
  • AK ASLAM Qazi Hussain Ahmad Medical Complex, Nowshera, Pakistan
  • L ALI Department of Gastroenterology, DHQ Hospital Mardan, Pakistan
  • A MASOOD Qazi Hussain Ahmad Medical Complex, Nowshera, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.642

Keywords:

Stool Antigen, Perforated Duodenal Ulcer, H-Pylori

Abstract

A cross-sectional study was conducted at the Department of Gastroenterology Qazi Hussein Ahmad Medical Complex, Nowshera, from January 2020 to January 2022 to determine the prevalence of H-pylori infection in patients with a perforated duodenal ulcer. A total of 189 patients were enrolled in the study. The data was analyzed using SPSS version 19 statistical software. Categorical data was computed as frequency and percentages and mean ± SD was used for all numerical variables. Out of the 189 patients, 115 (60.85%) were male and had an average age of 43.70 ± 7.38, and 74 (39.15%) were female and had an average age of 45.72 ± 8.85. The study revealed that 98 (51.85%) patients tested positive for H. Pylori stool antigen, while 91 (48.15%) tested negative. Based on the findings, patients with a perforated duodenal ulcer are more likely to have an infection with Helicobacter pylori. Therefore, it is crucial to conduct a thorough examination of such cases. Early diagnosis and treatment of H-pylori infection can prevent harmful consequences for the patient.

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References

Abro, A. H., Haider, I. Z., and Ahmad, S. (2011). Helicobacter pylori infection in patients with calcular cholecystitis: a hospital based study. Journal of Ayub Medical College Abbottabad 23, 30-33.

BJ, M. (1983). Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1, 1273-1275.

Blaser, M. J., Perez-Perez, G. I., Kleanthous, H., Cover, T. L., Peek, R. M., Chyou, P., Stemmermann, G. N., and Nomura, A. (1995). Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer research 55, 2111-2115.

Brandi, G., Biavati, B., Calabrese, C., Granata, M., Nannetti, A., Mattarelli, P., Di Febo, G., Saccoccio, G., and Biasco, G. (2006). Urease-positive bacteria other than Helicobacter pylori in human gastric juice and mucosa. Official journal of the American College of Gastroenterology| ACG 101, 1756-1761.

Ebrahim, A., and Balqis, A.-S. (2020). Helicobacter Pylori infection in Adult Patients with Non-Ulcer Dyspepsia. Al-Andalus Journal for Applied Sciences 7.

Gwee, K.-A., Teng, L., Wong, R.-K., Ho, K.-Y., Sutedja, D.-S., and Yeoh, K.-G. (2009). The response of Asian patients with functional dyspepsia to eradication of Helicobacter pylori infection. European journal of gastroenterology & hepatology 21, 327-334.

Hestvik, E., Tylleskar, T., Kaddu-Mulindwa, D. H., Ndeezi, G., Grahnquist, L., Olafsdottir, E., and Tumwine, J. K. (2010). Helicobacter pyloriin apparently healthy children aged 0-12 years in urban Kampala, Uganda: a community-based cross sectional survey. BMC gastroenterology 10, 1-9.

Khalifa, M. M., Sharaf, R. R., and Aziz, R. K. (2010). Helicobacter pylori: a poor man's gut pathogen? Gut pathogens 2, 1-12.

Malfertheiner, P., and Schulz, C. (2020). Peptic ulcer: chapter closed? Digestive Diseases 38, 112-116.

Marshall, B., and Warren, J. R. (1984). Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. The lancet 323, 1311-1315.

Megraud, F., Coenen, S., Versporten, A., Kist, M., Lopez-Brea, M., Hirschl, A. M., Andersen, L. P., Goossens, H., and Glupczynski, Y. (2012). Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption. Gut, gutjnl-2012-302254.

Newton, R., Ziegler, J. L., Casabonne, D., Carpenter, L., Gold, B. D., Owens, M., Beral, V., Mbidde, E., Parkin, D. M., and Wabinga, H. (2006). Helicobacter pylori and cancer among adults in Uganda. Infectious agents and cancer 1, 1-5.

Ogihara, A., Kikuchi, S., Hasegawa, A., Kurosawa, M., Miki, K., Kaneko, E., and Mizukoshi, H. (2000). Relationship between Helicobacter pylori infection and smoking and drinking habits. Journal of gastroenterology and hepatology 15, 271-276.

Tanih, N., Dube, C., Green, E., Mkwetshana, N., Clarke, A., Ndip, L., and Ndip, R. (2009). An African perspective on Helicobacter pylori: prevalence of human infection, drug resistance, and alternative approaches to treatment. Annals of Tropical Medicine & Parasitology 103, 189-204.

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Published

2023-12-31

How to Cite

NAEEM , M., AHMAD , S., ULLAH , H., MUJAHID, ., ASLAM , A., ALI , L., & MASOOD , A. (2023). PREVALENCE OF H. PYLORI INFECTION IN PATIENTS PRESENTING WITH PERFORATED DUODENAL ULCER. Biological and Clinical Sciences Research Journal, 2023(1), 642. https://doi.org/10.54112/bcsrj.v2023i1.642

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