PREDICTORS OF MORTALITY AND POOR FUNCTIONAL OUTCOME IN PATIENTS WITH ACUTE STROKE ADMITTED TO A TERTIARY CARE HOSPITAL IN PAKISTAN

S LUQMAN; A MUMTAZ; S KULSOOM; S  AHMED; A MALIK; SA HAIDER

doi:10.54112/bcsrj.v2023i1.281

Authors

S LUQMAN Department of Neurology, Quaid-e-Azam Medical College, Bahawalpur, Pakistan
A MUMTAZ Department of Neurology, Chandka Medical College Hospital & Shaheed Mohtarma Benazir Bhutto Medical University Larkana, Pakistan
S KULSOOM Department of Neurology, National Institute of Child Health Karachi, Pakistan
S AHMED Department of Neurology, Al Noor Specialist Hospital Makkah, Saudi Arabia
A MALIK Department of Neurology, Sharif Medical and Dental College Lahore, Pakistan
SA HAIDER Department of Neurology, Sharif Medical and Dental College Lahore, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.281

Keywords:

Predictors, Acute Ischemic Stroke, Morbidity, Mortality, Stroke

Abstract

Acute stroke is a major cause of morbidity and mortality worldwide, including Pakistan. Identifying the predictors of poor outcomes in acute stroke patients can help develop targeted interventions to improve patient outcomes. A retrospective chart review was conducted on 220 patients with acute stroke admitted to a tertiary care hospital in Pakistan between January 2022 and December 2022. The primary outcome measures were mortality and poor functional outcomes at discharge and 3-month follow-up. Logistic regression analyses were performed to identify independent predictors of these outcomes. Older age, higher NIHSS score at admission, and comorbidities like hypertension, diabetes mellitus, ischemic heart disease, and haemorrhagic stroke subtype were significant predictors of mortality and poor functional outcome. Longer hospital stays and lack of intravenous thrombolysis were also associated with poor functional outcomes. Of the 220 patients with acute stroke, 62 (28.2%) died during their hospital stay. 136 (61.8%) patients had poor functional outcomes at discharge, increasing to 161 (73.2%) at 3-month follow-up. This study identified several predictors of poor outcomes in acute stroke patients admitted to a tertiary care hospital in Pakistan. Early identification and management of modifiable risk factors, including comorbidities and stroke subtypes, may help improve outcomes in these patients.

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