ANTIBIOTIC PRESCRIPTION AND ANTIMICROBIAL RESISTANCE RATES OF UROPATHOGENS IN CHILDREN WITH URINARY TRACT INFECTIONS

M ADNAN; . SAIFULLAH; MAH KHAN; M HUSSAIN; F HAMAYUN; G KHAN

doi:10.54112/bcsrj.v2023i1.263

Authors

M ADNAN Department of Urology, Bakhtawar Amin Trust Teaching Hospital Multan, Pakistan
. SAIFULLAH Department of Urology, Bakhtawar Amin Trust Teaching Hospital Multan, Pakistan
MAH KHAN Department of Urology, Bakhtawar Amin Trust Teaching Hospital Multan, Pakistan
M HUSSAIN Department of Urology, Sharif Medical and Dental College Lahore, Pakistan
F HAMAYUN Department of Pediatrics Urology, The Children's Hospital & Institute of Child Health Lahore, Pakistan
G KHAN Department of Urology, Gomal Medical College Dera Ismail Khan, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.263

Keywords:

Antibiotics, Antimicrobial Resistance, Pathogens, Urinary Tract Infections

Abstract

The current study aimed to evaluate the antibiotic treatment of UTIs and antimicrobial resistance of uropathogens in children with UTIs. A retrospective study was conducted in the Pediatrics Department of different centers from November 2021-November 2022. A total of 100 children with febrile or afebrile urinary tract infections were included in the study. UTIs were categorized as febrile and afebrile. Antibiotics were prescribed according to the UTI and pathogen identified. E.coli was the most common pathogen (80%) found in patients of both groups, while Citrobacter sp and gram-positive cocci were only found in one case each. Amikacin was mostly prescribed in both groups (54 for fUTIs and 8 for aUTIs). 60% of the E.coli isolates were resistant to ampicillin, 10% to AMC (amoxicillin and clavulanic acid), and 15% to SAM (Sulfacetamide sodium). The highest resistant rates of E.coli were observed against SXT, i.e., 25%. Based on the results, it can be concluded that there is a need for antimicrobial resistance stewardship programs to control the increasing prevalence of resistance among UTI-causing pathogens.

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