ENDOSCOPIC THIRD VENTRICULOSTOMY VS VENTRICULOPERITONEAL SHUNT IN OBSTRUCTIVE HYDROCEPHALUS IN TERMS OF POST-OPERATIVE COMPLICATIONS

Authors

  • MM SHAH Department of Neurosurgery, Rawalpindi Teaching Hospital Rawalpindi, Pakistan
  • M KHAN Department of General Surgery, Rawalpindi Teaching Hospital Rawalpindi, Pakistan
  • N AKHTAR Department of Neurosurgery, Rawalpindi Teaching Hospital Rawalpindi, Pakistan
  • A TASSADAQ Department of Neurosurgery, Rawalpindi Teaching Hospital Rawalpindi, Pakistan
  • Y SHAHZAD Department of Neurosurgery, Rawal Institute of Health Sciences Islamabad, Pakistan
  • I KHAN Department Of Neurosurgery, Kulsum International Hospital Islamabad, Pakistan
  • Z MASOOD Department Of Neurosurgery, Kulsum International Hospital Islamabad, Pakistan
  • Y ANWAR Department of Neurosurgery, Rawalpindi Teaching Hospital Rawalpindi, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2024i1.1222

Keywords:

Ventriculoperitoneal Shunt, Endoscopic Third Ventriculostomy, Obstructive Hydrocephalus, Cerebrospinal Fluid.

Abstract

: Obstructive Hydrocephalus is a condition characterized by increased cerebrospinal fluid (CSF) volume within the brain's ventricular system, leading to clinical deterioration and disability. Without treatment, it can be fatal. Two primary treatment modalities are Ventriculoperitoneal Shunting (VPS) and Endoscopic Third Ventriculostomy (ETV), with ongoing debate over the superiority of one approach over the other. Objective: To compare the complications associated with Ventriculoperitoneal Shunting (VPS) and Endoscopic Third Ventriculostomy (ETV) in patients with obstructive hydrocephalus. Methods: A randomized controlled trial was conducted at a tertiary care hospital from April 15, 2024, to September 15, 2024. A total of 100 patients diagnosed with obstructive hydrocephalus were randomly allocated into two groups: 50 patients received VPS treatment, and 50 received ETV. Complications, including surgical site infection, seizures, hematoma, and CSF leakage, were recorded and analyzed. Results: Complications were observed in 36% (n=18) of patients in the VPS group compared to 16% (n=8) in the ETV group, with a statistically significant difference (p=0.023). Surgical site infections occurred in 8% (n=4) of VPS patients, while no infections were reported in the ETV group. Seizures were significantly more common in the VPS group, affecting 26% (n=13) compared to 8% (n=4) in the ETV group (p=0.017). Hematoma formation was observed in 4% (n=2) of VPS patients and 6% (n=3) of ETV patients. CSF leakage occurred in 4% (n=2) of VPS patients and 2% (n=1) of ETV patients. Conclusion: Endoscopic Third Ventriculostomy (ETV) demonstrated a significantly lower complication rate compared to Ventriculoperitoneal Shunting (VPS) in the management of obstructive hydrocephalus. These findings support ETV as a safer alternative with fewer associated complications.

Downloads

Download data is not yet available.

References

Koleva M, De Jesus O. Hydrocephalus. [Updated 2023 Jul 24]. StatPearls [Internet]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560875/

Nelson S. Hydrocephalus [Internet]. Medscape. 2023 [cited 2023 Nov 15]. Available from: https://emedicine.medscape.com/article/1135286-overview

Greenberg M. Hydrocephalus General Aspects. Greenberg Handbook of Neurosurgery. 2023;10. 426-451.

Lu L, Chen H, Weng S, Xu Y. Endoscopic Third Ventriculostomy versus Ventriculoperitoneal Shunt in Patients with Obstructive Hydrocephalus: Meta-Analysis of Randomized Controlled Trials. World Neurosurg. 2019;129:334-340.

Jiang L, Gao G; Zhou Y. Endoscopic third ventriculostomy and ventriculoperitoneal shunt for patients with noncommunicating hydrocephalus: A PRISMA-compliant meta-analysis. Medicine (Baltimore). 2018;97(42):e12139.

Abdel-Aziz K, Nouby R, Thabet M, Elshirbiny M. Endoscopic third ventriculostomy versus ventriculoperitoneal shunt for infant hydrocephalus. Open J Mod Neurosurg. 2020;10(02):193–202.

Mousa A, Abdel-Aziz S, Mohammed M, Beltagy M, Melesy A. Endoscopic third ventriculostomy versus ventriculoperitoneal shunt in the treatment of obstructive hydrocephalus complicating pediatric posterior fossa tumors. Al-Azhar Med J.

Haq N, Ishaq M, Jalal A. Outcome comparison of endoscopic third ventriculostomy versus ventriculoperitoneal shunt in obstructive hydrocephalus. Pak J Med Health Sci. 2022;16(2):956–8.

Simair I, Ali H, Qureshi A, Salah-ud-Din T. Outcome comparison of endoscopic third ventriculostomy versus ventriculoperitoneal shunt in obstructive hydrocephalus. Pak J Neurol Surg. 2021;25(3):324–30.

Uche, E.O., Okorie, C., Iloabachie, I. et al. Endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS) in non-communicating hydrocephalus (NCH): comparison of outcome profiles in Nigerian children. Childs Nerv Syst 34, 1683–1689 (2018). https://doi.org/10.1007/s00381-018-3848-0

Bouras T, Sgouros S. Complications of Endoscopic Third Ventriculostomy. World Neurosurg. (2013) 79, 2S:S22.e9-S22.e12. DOI: 10.1016/j.wneu.2012.02.014.

Mushtaq et al. Effectiveness of Endoscopic Third Ventriculostomy Versus Ventriculo-Peritoneal Shunt in Obstructive Hydrocephalus. Pak. J. of Neurol. Surg. – 2024 – 28 (3): 297-305.

Mersha H. Endoscopic third ventriculostomy versus ventriculoperitoneal shunt placement in children with obstructive hydrocephalus. East Cent Afr J Surg. 2017;22(3):11-20.

Sharafat S, Khan Z, Azam F, Ali M. Frequency of success and complications of primary endoscopic third ventriculostomy in infants with obstructive hydrocephalous. Pak J Med Sci. 2022;38(1):267-270

Rahman MM, Salam MA, Uddin K, Rahman MM, Islam MR, Haque MA, et al. Early surgical outcome of endoscopic third ventriculostomy in the management of obstructive hydrocephalus: A randomized control trial. Asian J Neurosurg 2018;13:1001-4

Kamikawa S, Inui A, Kobayashi N, Kuwamura K, Kasuga M, Yamadori T, Tamaki N. Endoscopic treatment of hydrocephalus in children: a controlled study using newly developed Yamadori-type ventriculoscopes. Minim Invasive Neurosurg. 2001 Mar;44(1):25-30. doi: 10.1055/s-2001-13587. PMID: 11409308.

Kong et al. Endoscopic Third Ventriculostomy vs. Ventriculoperitoneal Shunt for Obstructive Hydrocephalus: A Meta-Analysis of Randomized Controlled Trials. Turk Neurosurg 33(6):960-966, 2023. DOI: 10.5137/1019-5149.JTN.40204-22.2.

Navaei AA, Hanaei S, Habibi Z, Jouibari MF, Heidari V, Naderi S, et al. Controlled trial to compare therapeutic efficacy of endoscopic third ventriculostomy plus choroid plexus cauterization with ventriculoperitoneal shunt in infants with obstructive hydrocephalus. Asian J Neurosurg 2018;13:1042-7.

Downloads

Published

2024-10-26

How to Cite

SHAH , M., KHAN , M., AKHTAR , N., TASSADAQ , A., SHAHZAD , Y., KHAN , I., MASOOD , Z., & ANWAR , Y. (2024). ENDOSCOPIC THIRD VENTRICULOSTOMY VS VENTRICULOPERITONEAL SHUNT IN OBSTRUCTIVE HYDROCEPHALUS IN TERMS OF POST-OPERATIVE COMPLICATIONS. Biological and Clinical Sciences Research Journal, 2024(1), 1222. https://doi.org/10.54112/bcsrj.v2024i1.1222

Most read articles by the same author(s)

1 2 3 > >>