ASSESSMENT OF VITAMIN D AND CALCIUM LEVELS IN TYPE 2 DIABETES MELLITUS

U ASLAM; NR RAJPUT; N NIYAMAT; N ALI; M NADEEM; M BAIG

doi:10.54112/bcsrj.v2023i1.397

Authors

U ASLAM Department of Medicine, FJMU/SGRH Lahore, Pakistan.
NR RAJPUT Department of Medicine, Sahara Medical College, Pakistan
N NIYAMAT Department of Medicine, FJMU/SGRH Lahore, Pakistan.
N ALI Department of Medicine, FJMU/SGRH Lahore, Pakistan.
M NADEEM Department of Medicine, FJMU/SGRH Lahore, Pakistan.
M BAIG Department of Medicine, FJMU/SGRH Lahore, Pakistan.

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.397

Keywords:

25 hydroxy Vitamin D, calcium, Type 2 diabetes mellitus

Abstract

Diabetes mellitus is an endocrinological condition marked by poor carbohydrate metabolism. T2DM is increasing both domestically and globally. Vitamin D and calcium have a significant role in intermediate metabolic processes, which include enzyme activity, electrical gradients, and the functioning of cells. T2DM was shown to be correlated with abnormal calcium and vitamin D levels. The objective of the current study is to assess the calcium and vitamin D levels in 200 patients, of whom 100 were T2DM patients and 100 were healthy, non-diabetic controls. 12 hours of entire night fasting, a volume of 5 ml of blood was drawn completely aseptically from the antecubital vein to measure glycated hemoglobin, fasting plasma glucose (FPG), postprandial plasma glucose (PPPG), serum 25 hydroxy (OH) Vitamin D (25[OH]D) and calcium. There was a statistically significant difference between the type 2 diabetes and non-diabetic groups for the following measurements: FPG (P 0.001), PPPG (P 0.001), serum vitamin D (P 0.001), and calcium (P 0.001). Comparing T2DM patients to the control group, lower calcium and vitamin D levels were found. This study found that Type 2 diabetes patients had much lower vitamin D and calcium levels, which may play a key role in the disease's propensity to develop early in vulnerable people.

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