FREQUENCY OF MICROALBUMINURIA IN TYPE II DIABETES MELLITUS PATIENTS: A CROSS SECTIONAL STUDY

Authors

  • J SAJJAD Nawaz Shareef Medical College, Aziz Bhatti Shaheed Teaching Hospital Gujrat, Pakistan
  • S WAHAB MTI DHQTH/Gomal Medical College, Dera Ismail Khan, Pakistan
  • S HIDAYAT Department of General Medicine, Khyber teaching Hospital, Peshawar, Pakistan
  • U ZAHID Department of Nephrology, Khyber Teaching Hospital Peshawar, Pakistan
  • HA ABDULLAH Department of Emergency, Hameed Latif Teaching Hospital Lahore, Pakistan
  • Z MUSHEER Department of Gynaecology and Obstetrics, Hameed Latif Teaching Hospital, Lahore, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2024i1.1440

Keywords:

Type II diabetes mellitus, microalbuminuria, hypertension, BMI, duration of diabetes, cross-sectional study, risk factors

Abstract

Microalbuminuria is an early marker of diabetic nephropathy and an important predictor of cardiovascular and renal complications in patients with Type II diabetes mellitus. Identifying its prevalence and associated risk factors is crucial for early intervention Objective: The objective of this study was to determine the frequency of microalbuminuria and its associated risk factors in patients with Type II diabetes mellitus. Methods: This cross-sectional study was carried out in the medical ward of a tertiary care hospital from March 2024 to September 2024. Two hundred fifty patients, aged 30 years or older, diagnosed with Type II diabetes, were selected. The presence of microalbuminuria was assessed using urine albumin-to-creatinine ratio measurements. Results: Mean age was 52.04 ± 12.311 years, gender-wise there were 152 males (60.8%) and 98 females (39.2%) patients. The frequency of microalbuminuria was 76 (30.4%). Microalbuminuria was notably associated with BMI, duration of diabetes, and the presence of hypertension, with significant associations observed (p < 0.05) for all these factors. Conclusion: Our study demonstrated that microalbuminuria was found in 30.4% of patients presenting with diabetes type II, with significant associations observed for hypertension, BMI, and the duration of diabetes.

Downloads

Download data is not yet available.

References

Galicia-Garcia U, Benito-Vicente A, Jebari S, Larrea-Sebal A, Siddiqi H, Uribe KB, et al. Pathophysiology of type 2 diabetes mellitus. International journal of molecular sciences. 2020;21(17):6275.

Bellary S, Kyrou I, Brown JE, Bailey CJ. Type 2 diabetes mellitus in older adults: clinical considerations and management. Nature Reviews Endocrinology. 2021;17(9):534-48.

Oguntibeju OO. Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links. International journal of physiology, pathophysiology and pharmacology. 2019;11(3):45.

Cherney DZ, Charbonnel B, Cosentino F, Dagogo-Jack S, McGuire DK, Pratley R, et al. Effects of ertugliflozin on kidney composite outcomes, renal function and albuminuria in patients with type 2 diabetes mellitus: an analysis from the randomised VERTIS CV trial. Diabetologia. 2021;64:1256-67.

Yamazaki T, Mimura I, Tanaka T, Nangaku M. Treatment of diabetic kidney disease: current and future. Diabetes & metabolism journal. 2021;45(1):11-26.

Warjukar P, Jain P, Kute P, Anjankar A, Ghangale S. Study of microalbuminuria and uric acid in type 2 diabetes mellitus. Int J Cur Res Rev. 2020;2020.

Shahwan M, Yasin H, Edis Z, Suliman A, Al-Azawi R, Mohammadi S, et al. Prevalence Of Diabetes, Hypertension And Obesity And Associated Factors Among Students Of Ajman University, United Arab Emirates. The International Research Journal of Pharmacy. 2019;10(5):64-7.

Chiu W-C, Lai Y-R, Cheng B-C, Huang C-C, Chen J-F, Lu C-H. HbA1C variability is strongly associated with development of macroalbuminuria in normal or microalbuminuria in patients with type 2 diabetes mellitus: a six‐year follow‐up study. BioMed research international. 2020;2020(1):7462158.

Sarafidis PA, Bakris GL. Microalbuminuria and chronic kidney disease as risk factors for cardiovascular disease. Nephrology Dialysis Transplantation. 2006;21(9):2366-74.

Verma MK, Kumar P, Sharma P, Singh V, Singh SP. Study of microalbuminuria as early risk marker of nephropathy in type 2 diabetic subjects. Int J Res Med Sci. 2017;5(7):3161-6.

Chowta N, Pant P, Chowta M. Microalbuminuria in diabetes mellitus: Association with age, sex, weight, and creatinine clearance. Indian journal of nephrology. 2009;19(2):53-6.

AlFehaid AA. Prevalence of microalbuminuria and its correlates among diabetic patients attending diabetic clinic at National Guard Hospital in Alhasa. Journal of Family and Community Medicine. 2017;24(1):1-5.

Sana MA, Chaudhry M, Malik A, Iqbal N, Zakiuddin A, Abdullah M. Prevalence of microalbuminuria in type 2 diabetes mellitus. Cureus. 2020;12(12).

Pasko N, Toti F, Zekollari E, Strakosha A, Kacori V, Thereska N. Prevalence of microalbuminuria in type 2 diabetes patients in Tirana, a preliminary multicenter study. Journal of Diabetes Mellitus. 2013;3(3):145-9.

Downloads

Published

2024-12-30

How to Cite

SAJJAD, J., WAHAB, S., HIDAYAT, S., ZAHID, U., ABDULLAH , H., & MUSHEER, Z. (2024). FREQUENCY OF MICROALBUMINURIA IN TYPE II DIABETES MELLITUS PATIENTS: A CROSS SECTIONAL STUDY. Biological and Clinical Sciences Research Journal, 2024(1), 1440. https://doi.org/10.54112/bcsrj.v2024i1.1440