UTERINE ARTERY DOPPLER INDICES AS PREDICTIVE MEASURES FOR THE PRE-ECLAMPSIA AND INTRAUTERINE GROWTH RESTRICTION

Authors

  • MN Rashid University Institute of Radiological Sciences and Medical Imaging Technology, The University of Lahore, Lahore, Pakistan
  • M Kari Fatima Jinnah Medical University, Lahore, Pakistan
  • R Rashid University Institute of Radiological Sciences and Medical Imaging Technology, The University of Lahore, Lahore, Pakistan
  • MA Rana Intensive Care Unit, Bahria International Hospital, Lahore, Pakistan
  • A Amjad PSRD College of Rehabilitation Sciences, Sialkot, Pakistan
  • MM Hafeez Institute of Molecular Biology & Biotechnology, University of Lahore, Lahore, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2020i1.23

Keywords:

Pre-eclampsia, Intrauterine growth restriction, Uterine artery Doppler ultrasonography, hypertension, pregnancy

Abstract

Preeclampsia and Intrauterine growth restriction (IUGR) remains as the important causes for the neonatal and maternal complications leading to even death in some cases. Uterine artery Doppler USG can be done transvaginally or trans abdominal and performed in the 1st or 2nd trimester of the pregnancy to detect these complications Doppler waveform suggested the high vascular resistance to blood flow. In our present study, we conclude uterine artery Doppler indices as prognostic procedure for the preeclampsia and intrauterine growth restriction. A cross-sectional survey design with convenient sampling technique was used. Mixture of standardized and self-modified structured questionnaire was undertaken to determine the indices of pre eclampsia and IUGR by uterine artery. The data was collected from Bahria International Hospital, Lahore during the period of 9 months. This study was included 162 pregnant females with identification of the main uterine artery on a longitudinal scan lateral to the uterus.  Initial diastolic notch of right and left side of the uterine artery waveforms was recorded. At every antenatal checkup, urine was tested for protein and blood pressure readings were taken to identify preeclampsia. Further analysis was done dividing patients as normotensive and those patients developing hypertension after 30 weeks of gestation. After delivery neonates observed for IUGR by head circumference and body weight. The study was concluded that from the total sample size of 162 pregnant females who undergoes uterine artery Doppler, 34% females shows diastolic notch and almost all of these later diagnosed with preeclampsia and 19.8% deliver babies with IUGR. So, based on the study, we have concluded that uterine artery Doppler is helpful to provide diagnosis of preeclampsia and IUGR in early pregnancy.

Downloads

Download data is not yet available.

References

Albu, A.R., Anca, A.F., Horhoianu, V.V., Horhoianu, I.A. (2014). Predictive factors for intrauterine growth restriction. Journal of Medicine and Life. 7(2):165.

Anastasakis, E., Paraskevas, K.I., Papantoniou, N., Daskalakis, G., Mesogitis, S., Mikhailidis, D.P., Antsaklis, A. (2008). Association between abnormal uterine artery Doppler flow velocimetry, risk of preeclampsia, and indices of arterial structure and function: a pilot study. Angiology. 59(4):493-9.

Azhar S, Huma Ze, Mahmood N, Azhar M, Hafeez MM, Azhar M, Malik A. (2020). comparison of predictive accuracy of transcerebellar diameter to abdominal circumference ratio (TCD/AC) versus head circumference to abdominal circumference ratio (hc/ac) in intrauterine growth restriction on ultrasonography. Inter. J. Biol. Pharm. Allied Sci.9; 4: 114-.123.

Berkley, E., Chauhan, S.P., Abuhamad, A, (2012). Society for Maternal-Fetal Medicine Publications Committee. Doppler assessment of the fetus with intrauterine growth restriction.American journal of obstetrics and gynecology. 206(4):300-8.

Caradeux, J., Martinez-Portilla, R.J., Peguero, A., Sotiriadis, A., Figueras, F. (2019). Diagnostic Performance of Third Trimester Ultrasound for the Prediction of Late-Onset Fetal Growth Restriction: A Systematic Review and Meta-Analysis. American Journal of Obstetrics and Gynecology. 8.

Ciobanu, A., Rouvali, A., Syngelaki, A., Akolekar, R., Nicolaides, KH. (2019). Prediction of small for gestational age neonates: screening by maternal factors, fetal biometry, and biomarkers at 35–37 weeks‟ gestation. American Journal of Obstetrics and Gynecology. 220(5):486-e1.

Cnossen, J.S., Morris, R.K., Terriet, G., Mol, B.W., van der Post, J.A., Coomarasamy, A., Zwinderman, A.H., Robson, S.C., Bindels, P.J., Kleijnen, J., Khan, K.S. (2008). Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis. Canadian Medical Association Journal. 178(6):701-11.

Damodaram, M., Story, L, .Eixarch, E., Patel, A, McGuinness A, Allsop J, Wyatt-Ashmead, J., Kumar, S., Rutherford, M. (2010). Placental MRI in intrauterine fetal growth restriction. Placenta. 31(6):491-8.

Finn-Sell, S.L., Cottrell, E.C., Greenwood, S.L., Dilworth, M.R., Cowley, E.J., Sibley, C.P., Wareing, M. (2018). Pomegranate Juice Supplementation Alters Utero-placental Vascular Function and Fetal Growth in the eNOS-/-Mouse Model of Fetal Growth Restriction. Frontiers in Physiology. 9:1145.

Harman, C.R., Baschat, A.A. (2003). Comprehensive assessment of fetal wellbeing: which Doppler tests should be performed? Current Opinion in Obstetrics and Gynecology. 15(2):147-57.

Janwantanakul, P., Pensri, P., Jiamjarasrangsri, V., and Sinsongsook, T. (2008). Prevalence of self-reported musculoskeletal symptoms among office workers. Occupational Medicine 58, 436-438.

Litwińska, E., Litwińska, M., Oszukowski, P., Szaflik, K., Kaczmarek, P. (2017). Combined screening for early and late pre-eclampsia and intrauterine growth restriction by maternal history, uterine artery Doppler, mean arterial pressure and biochemical markers. Advances in Clinical and Experimental Medicine. 26(3):439-48.

MacDonald, T.M., McCarthy, E.A., Walker SP. (2015). Shining light in dark corners: Diagnosis and management of late‐onset fetal growth restriction. Australian and New Zealand Journal of Obstetrics and G4naecology. 55(1):3-10.

Malik A, Hafeez MM, Mansoor G, Alam R, Waqar S, Shafique H, Zahid A, Parveen G, Razzaq A, Ali Q. (2018). Interrelationship of circulating biohemical variables of medical importance and their role in the pathogenis of prostate cancer. Inter. J. Biol. Pharm. Allied Sci.7; 7: 1291-1304.

Malik A, Khan Mi, Hafeez Z, Zubair A, Hafeez MM, Chaudhary HRZ, Nazar W, Waquar S. (2020). Role of vitamin d and oxidative stress markers in the development and progression of type 2 diabetes mellitus. Inter. J. Biol. Pharm. Allied Sci.9; 4: 613-6.26.

Pialis, A., Souka, P., Antsaklis, P. et al. (2007). Screening for pre-eclampsia and fetal growth restriction by uterine artery doppler and PAPP-A at 11-14 weeks gestation. Ultrasound Obstet Gynecol. 29: 135-140.

Seyam, Y.S., Al‐Mahmeid, M.S., Al‐Tamimi, H.K. (2002). Umbilical artery Doppler flow velocimetry in intrauterine growth restriction and its relation to perinatal outcome. International Journal of Gynecology & Obstetrics. 77(2):131-7.

Turk, E.A., Stout, J.N., Ha, C., Luo, J., Gagoski, B., Yetisir, F., Golland, P., Wald, L.L., Adalsteinsson, E., Robinson, J.N., Roberts, D.J. (2019). Placental MRI: Developing Accurate Quantitative Measures of Oxygenation. Topics in Magnetic Resonance Imaging, 28(5):285-97.

Yamaleyeva, L,M., Brosnihan, K.B., Smith, L.M., Sun, Y. (2018). Preclinical Ultrasound-Guided Photoacoustic Imaging of the Placenta in Normal and Pathologic Pregnancy.Molecular imaging. 16;17:1-5.

Downloads

Published

2020-12-12

How to Cite

Rashid, M., Kari, M., Rashid, R., Rana, M., Amjad, A., & Hafeez, M. (2020). UTERINE ARTERY DOPPLER INDICES AS PREDICTIVE MEASURES FOR THE PRE-ECLAMPSIA AND INTRAUTERINE GROWTH RESTRICTION. Biological and Clinical Sciences Research Journal, 2020(1). https://doi.org/10.54112/bcsrj.v2020i1.23

Issue

Section

Original Research Articles

Most read articles by the same author(s)

<< < 1 2 3 4 > >>