Frequency of Acute Ischemic Mitral Regurgitation Among Patients of Acute Inferior ST-Elevation Myocardial Infarction Presenting at Tertiary Care Hospital

Kaleem Ullah; Muhammad Asif Iqbal; Irum Rehmat; Shah Fahad Ullah; Usman Shaharyar; Haider Sami; Sohail Ahmad

doi:10.54112/bcsrj.v6i6.2291

Authors

Kaleem Ullah Department of Cardiology, MTI-LRH, Peshawar, Pakistan
Muhammad Asif Iqbal Department of Cardiology, MTI-LRH, Peshawar, Pakistan
Irum Rehmat Department of Cardiology, MTI-LRH, Peshawar, Pakistan
Shah Fahad Ullah Department of Cardiology, MTI-LRH, Peshawar, Pakistan
Usman Shaharyar Department of Cardiology, MTI-LRH, Peshawar, Pakistan
Haider Sami Department of Cardiology, MTI-LRH, Peshawar, Pakistan
Sohail Ahmad Department of Cardiology, MTI-LRH, Peshawar, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v6i6.2291

Keywords:

Ischemic mitral regurgitation, inferior wall myocardial infarction, ST-elevation myocardial infarction, echocardiography, vena contracta

Abstract

Acute ischemic mitral regurgitation is an important mechanical complication of acute myocardial infarction and may worsen hemodynamic status and clinical outcomes. Inferior wall ST-elevation myocardial infarction may particularly affect papillary muscle function, increasing the risk of mitral regurgitation. Objective: To determine the frequency of acute ischemic mitral regurgitation (IMR) among patients of acute inferior ST- elevation myocardial infarction (IW- STEMI) presenting at tertiary care hospital. Methods: This study enrolled 124 patients who were older than 18 years, both male and female, presenting with acute inferior ST-elevation myocardial infarction in the Department of Cardiology, Lady Reading Hospital, Peshawar from 26-January-2025 to 26-April 2025. Those with previous mixed valvular heart disease, pre-existing mitral regurgitation and congenital heart disease were excluded. After standard treatment patients underwent transthoracic echocardiography. Ischemic mitral regurgitation was diagnosed by the presence of reverse flow across the mitral valve. Data was analyzed using SPSS 20. Results: The mean age of 124 patients in the current study was 56.56±10.48 years. Males were 83 (66.9%). Acute ischemic mitral regurgitation was diagnosed in 23 (18.5%) patients. Mild severity of IMR was observed in 15 (65.2%) cases, moderate in 6 (26.1%) and severe in 2 (8.7%) cases. Male gender showed a significant association with IMR (p=0.024). Conclusion: The frequency of acute ischemic mitral regurgitation (IMR) among patients of acute inferior ST- elevation myocardial infarction (IW- STEMI) was 18.5%, majority of the patients had mild IMR 65.2%. Male gender was significantly associated with IMR.

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