Efficacy of Phenol Injection in the Management of Pilonidal Sinus Among Patients Attending Saidu Group of Teaching Hospital

Mehran  Shah; Anwar Ul  Haque

doi:10.54112/bcsrj.v6i6.2111

Authors

Mehran Shah Department of General Surgery, Saidu Group of Teaching Hospital, Swat, Pakistan
Anwar Ul Haque Department of General Surgery, Saidu Group of Teaching Hospital, Swat, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v6i6.2111

Keywords:

Pilonidal sinus, phenol injection, minimally invasive, efficacy, wound healing, diabetes, sociodemographic factors

Abstract

Pilonidal sinus disease is an inflammatory condition characterized by a high tendency to recur. Objective: To determine the efficacy of phenol injection in treatment of pilonidal sinus in patients presenting at Saidu group of teaching hospital. Methodology: This study was carried out on 97 patients, aged 18 to 65 years with pilonidal sinus. All patients underwent phenol injection procedure under local anaesthesia, which involved sinus tract dilation of 3mm diameter, debridement, and the application of crystalline phenol. Efficacy of the treatment was assessed after 15 days of the procedure, in terms of e presence of granulation tissues, and collagen deposition. SPSS 27 was used for analyzing the gathered data. Results: The cohort in this study had a mean age 31.81 ± 14.50 years, and 54.6% male majority. The efficacy rate of the treatment was 84.5%. Efficacy demonstrated a positive significant association with younger age (p < 0.001) and urban residence (p = 0.03). Lower efficacy was observed in patients with diabetes mellitus (p < 0.001).Conclusion: Phenol injection is an effective treatment for pilonidal sinus disease, demonstrating a high efficacy rate (84.5%). Older patients, rural residents and patients with higher BMI exhibited lower efficacy rates.

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References

Mahmood F, Hussain A, Akingboye A. Pilonidal sinus disease: review of current practice and prospects for endoscopic treatment. Ann Med Surg (Lond). 2020;57:212–217. https://doi.org/10.1016/j.amsu.2020.06.013

Bi S, Sun K, Chen S, Gu J. Surgical procedures in pilonidal sinus disease: a systematic review and network meta-analysis. Sci Rep. 2020;10(1):13720. https://doi.org/10.1038/s41598-020-70727-5

Luedi MM, Schober P, Stauffer VK, Diekmann M, Andereggen L, Doll D. Gender-specific prevalence of pilonidal sinus disease over time: a systematic review and meta-analysis. ANZ J Surg. 2021;91(7–8):1582–1587. https://doi.org/10.1111/ans.17005

Kanlioz M, Ekici U, Tatli F, Karatas T. Pilonidal sinus disease: an analysis of the factors affecting recurrence. Adv Skin Wound Care. 2021;34(2):81–85. https://doi.org/10.1097/01.ASW.0000739176.15968.07

Almajid FM, Alabdrabalnabi AA, Almulhim KA. The risk of recurrence of pilonidal disease after surgical management. Saudi Med J. 2017;38(1):70–74. https://doi.org/10.15537/smj.2017.1.15892

Albabtain IT, Alkhaldi A, Aldosari L, Alsaadon L. Pilonidal sinus disease recurrence at a tertiary care center in Riyadh. Ann Saudi Med. 2021;41(3):179–185. https://doi.org/10.5144/0256-4947.2021.179

Kober MM, Alapati U, Khachemoune A. Treatment options for pilonidal sinus. Cutis. 2018;102(4):E23–E29.

Yilmaz TU, Yavuz O, Yirmibesoglu AO, Sarisoy HT, Vural C, Kiraz U, et al. Radiological, clinical, and histological findings in the treatment of pilonidal sinus with phenol injection. Medeni Med J. 2022;37(1):29–35. https://doi.org/10.4274/MMJ.galenos.2022.22566

Gan XX, Liu P, Chen SH, Li J, Zhao X, Chen W, et al. A meta-analysis comparing phenol treatment with surgical excision for pilonidal sinus. Asian J Surg. 2024;47(1):8–15. https://doi.org/10.1016/j.asjsur.2023.06.111

Girgin M, Kanat BH. The results of a one-time crystallized phenol application for pilonidal sinus disease. Indian J Surg. 2014;76(1):17–20. https://doi.org/10.1007/s12262-012-0548-y

Raza AA, Cheema UE, Ghaffar S, Ghani RA, Tahir S, Sajid M, et al. Comparison of the treatment of pilonidal sinus using phenol injection versus wide excision with secondary healing. Prof Med J. 2022;29(7):959–963. https://doi.org/10.29309/TPMJ/2022.29.07.6789

Alharbi M, Mujled HA. Phenol treatment for pilonidal sinus: systematic review. World J Surg Surg Res. 2019;2:1155. https://doi.org/10.25107/2637-4625.1155

Kilic AB, Muti Acar MN, Kilic S, Ekingen G. Evaluation of phenol treatment for pilonidal sinus in adolescents. Front Pediatr. 2025;13:1595749. https://doi.org/10.3389/fped.2025.1595749

Gozukucuk A, Cakiroglu B, Yapici S, Cesur IB, Ozcelik Z, Kilic HH. Comparing crystallized phenol and surgical excision treatments in pilonidal sinus disease. J Coll Physicians Surg Pak. 2022;32(5):652–657. https://doi.org/10.29271/jcpsp.2022.05.652

Emiroglu M, Karaali C, Esin H, Akpinar G, Aydin C. Treatment of pilonidal disease by phenol application. Turk J Surg. 2017;33(1):5–9. https://doi.org/10.5152/UCD.2016.3532

Demir M, Bölük SE, Sücüllü I, Güleç B, Bölük S. Efficacy of crystallized and liquid form phenol application in pilonidal sinus disease: a single-center retrospective study. Tech Coloproctol. 2025;29(1):109. https://doi.org/10.1007/s10151-025-03143-1

Dogru O, Camci C, Aygen E, Girgin M, Topuz O. Pilonidal sinus treated with crystallized phenol: an eight-year experience. Dis Colon Rectum. 2004;47(11):1934–1938. https://doi.org/10.1007/s10350-004-0720-y