Frequency of Depression in Young Patients with Diabetes Mellitus

. Abdullah; Tariq  Hussain

doi:10.54112/bcsrj.v6i5.1725

Authors

. Abdullah Department of Medicine Pakistan Atomic Energy Commission General Hospital Islamabad, Pakistan
Tariq Hussain Department of Medicine Pakistan Atomic Energy Commission General Hospital Islamabad, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v6i5.1725

Keywords:

Depression, Diabetes Mellitus, Glycemic Control, Hypertension, Mental Health Screening, Socioeconomic Status, Young Adults

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder associated with numerous physical and psychological complications. Depression is a common comorbidity in diabetic patients, significantly impacting self-care, glycemic control, and quality of life. Objective: To determine the frequency of depression in young patients with diabetes mellitus aged 15–45 years. Methods: This descriptive cross-sectional study was conducted at the Department of Medicine, PAEC General Hospital Islamabad from October 2024 till March 2025. A total of 122 diabetic patients aged 15–45 years, with a duration of diabetes over six months, were enrolled through non-probability consecutive sampling. Sociodemographic and clinical data were collected using a structured proforma. Results: Among 122 patients, 49 (40.2%) were diagnosed with depression. Depression was more common among females (45.3%) than males (34.5%). It was more prevalent in patients with lower income (<25,000 PKR/month: 57.9%), illiterate individuals (72.2%), and those with longer diabetes duration (>10 years: 52%). Higher rates were also observed among smokers (54.8%) and those with hypertension (50%). Depression severity ranged from mild (15.6%) to moderate (14.8%) and severe (9.8%). Significant associations were found between depression and income (p=0.01), education level (p=0.003), smoking (p=0.04), and hypertension (p=0.05). Conclusion: Depression is highly prevalent among young patients with diabetes, particularly those with lower socioeconomic status, poor education, and longer disease duration. Routine mental health screening and integrated psychological support should be incorporated into diabetes management to improve overall outcomes.

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References

Ogle GD, James S, Dabelea D, Pihoker C, Svennson J, Maniam J, et al. Global estimates of incidence of type 1 diabetes in children and adolescents: Results from the international diabetes federation atlas, 10th edition. Diabetes Res Clin Pract. 2022;183:109083.

Ismail M, Seif MH, Metwally N, Neshnash M, Joudeh AI, Alsaadi M, et al. Prevalence and determinants of depression among patients with Type 2 diabetes mellitus attending family medicine clinics in Qatar. Am J Med Open. 2023;9:100014.

Chen Z, Wang J, Carru C, Coradduzza D, Li Z. The prevalence of depression among parents of children/ adolescents with type 1 diabetes: A systematic review and meta-analysis. Front Endocrinol. 2023;14:1095729.

Mendes R, Martins S, Fernandes L. Adherence to medication, physical activity and diet in older adults with diabetes: its association with cognition, anxiety and depression. J Clin Med Res. 2019;11(8):583–92.

Tran NMH, Nguyen QNL, Vo TH, Le TTA, Ngo NH. Depression among patients with type 2 diabetes mellitus: prevalence and associated factors in Hue City, Vietnam. Dovepress. 2021;14:505—513.

Saenz JL, Villarreal VR. Prevalence of depression among adults with diabetes mellitus and the relationship between improvement in depressive symptoms and glycemic control. Cureus. 2023;15(11):e48241.

Khaledi M, Haghighatdoost F, Feizi A, Aminorroaya A. The prevalence of comorbid depression in patients with type 2 diabetes: an updated systematic review and meta-analysis on huge number of observational studies. Acta Diabetol. 2019;56(6):631–50.

Alajmani DSA, Alkaabi AM, Alhosani MW. Prevalence of undiagnosed depression in patients with type 2 diabetes. Front Endocrinol (Lausanne). 2019;10:259.

Işık AC, Akın S. Determination of diabetic patients’ depression prevalence and comparison of demographic and complications with healthy control. J Surg Med. 2021;5(2):179-82.

Roberts, A.J., Bao, H., Qu, P., Moss, A., Kim, G., Yi-Frazier, J.P., Pihoker, C. and Malik, F., 2021. Mental health comorbidities in adolescents and young adults with type 2 diabetes. Journal of pediatric nursing, 61, pp.280-283.

Regenold, William T., Ramesh K. Thapar, Christopher Marano, Sridevi Gavirneni, and Prasad V. Kondapavuluru. "Increased prevalence of type 2 diabetes mellitus among psychiatric inpatients with bipolar I affective and schizoaffective disorders independent of psychotropic drug use." Journal of affective disorders 70, no. 1 (2002): 19-26.

Morrato, E.H., Hill, J.O., Wyatt, H.R., Ghushchyan, V. and Sullivan, P.W., 2007. Physical activity in US adults with diabetes and at risk for developing diabetes, 2003. Diabetes care, 30(2), pp.203-209.

Moulton, Calum D., John C. Pickup, and Khalida Ismail. "The link between depression and diabetes: the search for shared mechanisms." The lancet Diabetes & endocrinology 3, no. 6 (2015): 461-471.

Mohamed, R., Abdul Kadir, A. and Yaacob, L.H., 2012. A study on depression among patient with type 2 diabetes mellitus in North-Eastcoast Malaysia. International Journal of Collaborative Research on Internal Medicine & Public Health, 4(8), pp.1589-600.

Mathew, M., Abish, A., Kuriakose, A., Isaiah, J.R. and AM, K., 2013. Predictors of depression among patients with diabetes mellitus in Southern India. Asian journal of psychiatry, 6(4), pp.313-317.

Woon, Luke Sy-Cherng, Hatta Bin Sidi, Arun Ravindran, Paula Junggar Gosse, Roslyn Laurie Mainland, Emily Samantha Kaunismaa, Nurul Hazwani Hatta et al. "Depression, anxiety, and associated factors in patients with diabetes: evidence from the anxiety, depression, and personality traits in diabetes mellitus (ADAPT-DM) study." BMC psychiatry 20 (2020): 1-14.

Ishizawa, K., Babazono, T., Horiba, Y., Nakajima, J., Takasaki, K., Miura, J., Sakura, H. and Uchigata, Y., 2016. The relationship between depressive symptoms and diabetic complications in elderly patients with diabetes: analysis using the Diabetes Study from the Center of Tokyo Women's Medical University (DIACET). Journal of Diabetes and its Complications, 30(4), pp.597-602.

Saluja, G., Iachan, R., Scheidt, P.C., Overpeck, M.D., Sun, W. and Giedd, J.N., 2004. Prevalence of and risk factors for depressive symptoms among young adolescents. Archives of pediatrics & adolescent medicine, 158(8), pp.760-765.

Pompili M, Lester D, Innamorati M, De Pisa E, Amore M, Ferrara C, Tatarelli R, Girardi P. Quality of life and suicide risk in patients with diabetes mellitus. Psychosomatics. 2009 Jan 1;50(1):16-23.