PATTERN OF CLINICAL PRESENTATION AMONG INFERTILE HYPERPROLACTINEMIC FEMALES

MEHWISH; AK HIRA; U NAZ; U NAZ; AH SHEIKH; R MAZHAR

doi:10.54112/bcsrj.v2022i1.172

Authors

MEHWISH Department of Gynecology, Ruth Pfau Hospital / Civil Hospital Karachi, Pakistan
AK HIRA Department of Gynecology, Dow University Of Health Sciences / Civil Hospital Karachi, Pakistan
U NAZ Department of Gynecology, Dow University Of Health Sciences / Civil Hospital Karachi, Pakistan
U NAZ Department of Gynecology, Sindh Govt Qatar Hospital Karachi, Pakistan
AH SHEIKH Department of Gynecology, Dow University Of Health Sciences / Civil Hospital Karachi, Pakistan
R MAZHAR Department of Gynecology, Ruth Pfau Hospital / Civil Hospital Karachi, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2022i1.172

Keywords:

Hyperprolactinemia, , Female Infertility, Endocrine disorder

Abstract

The current prospective study was designed to assess the pattern of clinical presentation among infertile hyperprolactinemic females. This study was conducted at the Gynaecology Department Civil Hospital Karachi from March 2020 to Dec 2020. A total of 110 infertile women who visited the Gynaecology department of the hospital were included in the study. A sample of the subjects with regular menstrual cycles was collected on the second or third day after fasting for 8-12 hours overnight. Samples of the patients with irregular menstrual cycles or amenorrhea were collected randomly after overnight fasting. ELISA technique was used for quantifying serum prolactin. A total of 110 infertile women were evaluated, of which 58 (52.7%) were hyperprolactinemic. The clinical presentation included galactorrhea (27.5%) followed by a mixed presentation (22.4%), menstrual abnormalities(15.5%), recurrent abortion(8.6%), and hirsutism (3.4%).22.4% of patients were symptomless. The most common pattern of presentation of hyperprolactinemic infertility was galactorrhea; a larger sample was symptomless.

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