EXPLORING THE APPLICATIONS OF CRISPR-CAS9 IN REVOLUTIONIZING AGRICULTURE FOR FOOD SECURITY AND SUSTAINABILITY
DOI:
https://doi.org/10.54112/bcsrj.v2024i1.1412Keywords:
CRISPR-Cas9, Gene-editing, Crop improvement, Food security, Sustainable agricultureAbstract
CRISPR-Cas9 is a revolutionary gene-editing tool with the potential to transform agriculture by enabling precise modifications to plant genomes. This technology allows for the enhancement of critical crop traits, such as disease resistance, drought tolerance, and improved nutritional value, without introducing foreign DNA. It offers a faster, more cost-effective alternative to traditional breeding methods, contributing to food security in the face of climate challenges. One key application of CRISPR-Cas9 is its ability to improve crop resistance to pests and diseases, reducing reliance on chemical pesticides and promoting sustainable farming. It also holds promise for enhancing the nutritional content of crops and addressing global malnutrition. However, challenges remain, including ethical concerns, regulatory issues, and the need to assess the long-term environmental impacts of gene-edited crops. Despite these obstacles, CRISPR-Cas9 has the potential to revolutionize agriculture, and future research will focus on refining its precision and overcoming societal barriers. As these challenges are addressed, CRISPR-Cas9 could play a central role in developing resilient, sustainable crops for a growing global population.
Downloads
References
Abbas, A., Arshad, A., Rehman, A. U., Bukhari, M. S., and Zaman, S. (2024). Revolutionizing plant breeding programs with advancements in molecular marker-assisted selection. Bulletin of Biological and Allied Sciences Research 2024, 57.
Aljabali, A. A., El-Tanani, M., and Tambuwala, M. M. (2024). Principles of CRISPR-Cas9 technology: advancements in genome editing and emerging trends in drug delivery. Journal of Drug Delivery Science and Technology, 105338.
Arshad, A., Iqbal, M. A., Farooq, S., and Abbas, A. (2024). Genetic evaluation for seed yield and its component traits in sunflower (Helianthus annuus l.) using line × tester approach. Bulletin of Biological and Allied Sciences Research 2024, 63.
Barrangou, R., Fremaux, C., Deveau, H., Richards, M., Boyaval, P., Moineau, S., Romero, D. A., and Horvath, P. (2007). CRISPR provides acquired resistance against viruses in prokaryotes. Science 315, 1709-1712.
Bhatti, M., Ahmad, S., Bilal, S., and Iqbal, M. (2023). Evaluation of different strains of entmopathogenic fungi as potential agents for the management of Tribolium castaneum. Bulletin of Biological and Allied Sciences Research 2023, 52-52.
Chen, K., Wang, Y., Zhang, R., Zhang, H., and Gao, C. (2019). CRISPR/Cas genome editing and precision plant breeding in agriculture. Annual review of plant biology 70, 667-697.
Falcon, W. P., Naylor, R. L., and Shankar, N. D. (2022). Rethinking global food demand for 2050. Population and Development Review 48, 921-957.
Fatima, S., CHEEMA, K., Shafiq, M., Manzoor, M., Ali, Q., Haider, M., and Shahid, M. (2023). The genome-wide bioinformatics analysis of 1-aminocyclopropane-1-carboxylate synthase (acs), 1-aminocyclopropane-1-carboxylate oxidase (aco) and ethylene overproducer 1 (eto1) gene family of fragaria vesca (woodland strawberry). Bulletin of Biological and Allied Sciences Research 2023, 38-38.
Gradziel, T. M. (2012). Traditional genetics and breeding. Genetics, genomics and breeding of crop plants, CRC Press, Boca Raton, 22-54.
Haider, M., Sami, A., Mazhar, H., Akram, J., NISA, B., Umar, M., and Meeran, M. (2023). Exploring morphological traits variation in Gomphrena globosa: A multivariate analysis. Biological and Agricultural Sciences Research Journal 2023, 21-21.
Hsu, P. D., Lander, E. S., and Zhang, F. (2014). Development and applications of CRISPR-Cas9 for genome engineering. Cell 157, 1262-1278.
Iqbal, U., Bashir, K., Khan, M., HASSAN, N., Jamil, S., Ullah, I., and Ullah, A. (2021). Cross-sectional study of covid-19 patients and their inflammatory markers in tertiary care hospitals of Peshawar, Pakistan. Bulletin of Biological and Allied Sciences Research 2021, 31-31.
Javed, M. M., Sami, A., Haider, M. Z., Abbas, A., Ali, M. H., Naeem, S., Amjad, M., Ahmad, A., and Bostani, R. (2024). The contribution of transgenic rice to enhance grain yield. Bulletin of Biological and Allied Sciences Research 2024, 65.
Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., and Charpentier, E. (2012). A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity. science 337, 816-821.
Junaid, M. D., and Gokce, A. F. (2024). Global agricultural losses and their causes. Bulletin of Biological and Allied Sciences Research 2024, 66.
Khan, S. H. (2019). Genome-editing technologies: concept, pros, and cons of various genome-editing techniques and bioethical concerns for clinical application. Molecular Therapy-Nucleic Acids 16, 326-334.
Lamichhane, J. R., Dachbrodt-Saaydeh, S., Kudsk, P., and Messéan, A. (2016). Toward a reduced reliance on conventional pesticides in European agriculture. Plant Disease 100, 10-24.
Liliane, T. N., and Charles, M. S. (2020). Factors affecting yield of crops. Agronomy-climate change & food security, 9.
Liu, Q., Yang, F., Zhang, J., Liu, H., Rahman, S., Islam, S., Ma, W., and She, M. (2021). Application of CRISPR/Cas9 in crop quality improvement. International Journal of Molecular Sciences 22, 4206.
Mushtaq, F., Akram, M. H., Usman, M., Mohsin, M., and Nawaz, M. S. (2024). Global climate change and its influence on crop production. Journal of Life and Social Sciences 2024, 27.
Ndudzo, A., Makuvise, A. S., Moyo, S., and Bobo, E. D. (2024). CRISPR-Cas9 genome editing in crop breeding for climate change resilience: Implications for smallholder farmers in Africa. Journal of Agriculture and Food Research, 101132.
Nie, H., Yang, X., Zheng, S., and Hou, L. (2024). Gene-Based Developments in Improving Quality of Tomato: Focus on Firmness, Shelf Life, and Pre-and Post-Harvest Stress Adaptations. Horticulturae 10, 641.
Pretty, J., and Bharucha, Z. P. (2014). Sustainable intensification in agricultural systems. Annals of botany 114, 1571-1596.
Rasheed, A., Gill, R. A., Hassan, M. U., Mahmood, A., Qari, S., Zaman, Q. U., Ilyas, M., Aamer, M., Batool, M., and Li, H. (2021). A critical review: recent advancements in the use of CRISPR/Cas9 technology to enhance crops and alleviate global food crises. Current Issues in Molecular Biology 43, 1950-1976.
Sen, H., Kumar, A., and Janeja, H. S. (2024). Biofortification of Major Crops through Conventional and Modern Biotechnological Approaches to Fight Hidden Hunger: An Overview. Journal of Advances in Biology & Biotechnology 27, 96-113.
Tester, M., and Langridge, P. (2010). Breeding technologies to increase crop production in a changing world. Science 327, 818-822.
Vondracek, K., Altpeter, F., Liu, T., and Lee, S. (2024). Advances in genomics and genome editing for improving strawberry (Fragaria× ananassa). Frontiers in Genetics 15, 1382445.
Yang, Y., and Hobbs, J. E. (2020). Supporters or opponents: will cultural values shape consumer acceptance of gene editing? Journal of Food Products Marketing 26, 17-37.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 A KARIM, SF AHMED, Z ASAD, T SARWER, A KANWAL, H SHAINA, A ISMAIL, S SHAUKAT, F MAJEED, ALK TIPU
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.