DISCORDANT CALCIUM AND PARATHYROID HORMONE WITH PRESUMED EPILEPTIC SEIZURES

M SALMAN; U AYMUN; S KHAWAR; B ASLAM; U ASLAM; T KHALID

doi:10.54112/bcsrj.v2023i1.314

Authors

M SALMAN Department of Pathology, Avicenna Medical College, Lahore, Pakistan
U AYMUN Department of Pathology, Avicenna Medical College, Lahore, Pakistan
S KHAWAR Department of Medicine, Gujranwala Teaching Hospital, Gujranwala, Pakistan
B ASLAM Department of Physiology, Independent Medical College, Faisalabad, Pakistan
U ASLAM Department of Medicine, Sir Gangaram Teaching Hospital, Lahore, Pakistan
T KHALID Department of Medicine, Jinnah Hospital, Lahore, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.314

Keywords:

parathyroid hormone, calcium levels, abnormalities in calcium

Abstract

Epileptic seizures are a neurological condition characterized by abnormal electrical activity in the brain, leading to involuntary and unpredictable movements, changes in consciousness, and other symptoms. The study's main objective is to find the discordant calcium and parathyroid hormone with presumed epileptic seizures. This study aims to investigate the association between discordant calcium and parathyroid hormone (PTH) levels and presumed epileptic seizures in a cohort of 200 patients. The study was conducted between June 2022 and December 2022. The study was conducted in collaboration with the neurology department. Patients admitted to the hospital with presumed epileptic seizures were included in the study. This study found that out % of the 200 patients who met the inclusion criteria, 65% had discordant calcium and PTH levels. Among these patients, 80% had low calcium and high PTH levels, while 20% had high calcium and low PTH levels. The logistic regression analysis showed a significant association between discordant calcium and PTH levels and presumed epileptic seizures (p<0.05). In conclusion, the results of this study suggest that abnormalities in calcium and parathyroid hormone (PTH) levels are not a major contributor to the development of epileptic seizures in most patients. While patients with hypocalcemia appeared to have a higher risk of seizures than those with normal calcium levels, most patients with hypocalcemia did not experience seizures.

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