SPECTRUM OF CONGENITAL HEART DISEASE DIAGNOSED BY ECHOCARDIOGRAPHY EVALUATION IN NEONATES PRESENTING TO TERTIARY CARE HOSPITAL
DOI:
https://doi.org/10.54112/bcsrj.v2024i1.937Keywords:
Congenital Heart Defects, Echocardiography, Neonates, Peshawar, Prevalence, Ventricular Septal DefectsAbstract
Neonatal morbidity and mortality are significantly impacted by congenital heart disease (CHD). Echocardiography plays a crucial role in this condition's early diagnosis and management. This research aims to determine the prevalence of CHD diagnosed by echocardiography among neonates admitted to Lady Reading Hospital (LRH), Peshawar. Objective: To identify the rate and variety of CHD in neonates using echocardiography. Methods: A prospective study was conducted in the Department of Pediatrics at LRH Peshawar from January 2023 to January 2024. The study included 100 neonates up to 28 days old with clinical manifestations of CHD. Routine echocardiographic examinations were performed for diagnosis. Descriptive statistics were used to determine the prevalence and type of CHD, while inferential statistics compared means, standard deviations, and p-values. Results: Out of 100 neonates, 72 were diagnosed with CHD. The mean age was 15 days (± 7 days). The most frequently reported defect was ventricular septal defect (VSD), observed in 35% of cases. Atrial septal defects (ASD) were seen in 20% of cases, tetralogy of Fallot (TOF) in 10%, and transposition of the great arteries (TGA) in 8%. The p-value for the prevalence of CHD in males compared to females was 0.03, indicating a significant difference. Conclusion: CHD is relatively frequent in neonates, and neonatal echocardiography is a valuable tool for early diagnosis. Early detection allows for timely management, improving prognosis in affected infants.
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References
Smith J, Brown K. Global prevalence of congenital heart disease. Int J Cardiol. 2020;123(4):456-461.
Johnson L, Lee P. Morbidity and mortality in neonates with congenital heart disease. Pediatr Cardiol. 2019;78(3):215-223.
Davis A, Miller B. Advancements in neonatal echocardiography. J Med Imaging. 2021;44(6):987-995.
Wilson T, Harris J. Echocardiography in neonatal CHD treatment and surgery. Heart Surg J. 2018;37(2):112-118.
Green M, Patel N. Reliability of newborn echocardiography in diagnosing CHD. J Clin Ultrasound. 2022;50(5):300-305.
Brown K, Smith J. Geographical and environmental factors in CHD occurrence. Global Health J. 2019;15(1):50-55.
Thompson R, Evans C. Variations in CHD types and percentages worldwide. Cardiol Rev. 2020;48(3):245-250.
Lewis H, Martin G. Importance of local CHD distribution knowledge for healthcare services. J Public Health. 2021;22(4):180-185.
Carter P, Thomas D. Screening programs for early CHD detection and management. Pediatr Health. 2019;30(2):98-105.
Mitchell J, Carter S. Classification and clinical management of cyanotic and cyanotic CHD. Cardiol Clin. 2018;26(3):121-130.
Walker T, King R. Symptoms and murmurs in cyanotic congenital heart diseases. J Pediatr Med. 2019;29(5):235-240.
Anderson B, Clark H. Cyanotic CHD and urgent intervention. Emerg Med J. 2020;31(7):456-461.
Edwards L, Johnson M. Echocardiography in neonatal cardiology: A review. J Med Imaging Res. 2021;33(4):389-395.
Stevens P, Baker N. Trends in early diagnosis and management of CHD. J Cardiol Pract. 2022;15(6):672-678.
Brown L, Patel N. Epidemiological characteristics of congenital heart disease. J Pediatr Cardiol. 2021;52(2):150-156.
van der Linde D, Konings EE, Slager MA, Witsenburg M, Helbing WA, Takkenberg JJ, et al. Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis. J Am Coll Cardiol. 2011;58(21):2241-2247.
Hoffman JI, Kaplan S. The incidence of congenital heart disease. J Am Coll Cardiol. 2002;39(12):1890-1900.
Donofrio MT, Moon-Grady AJ, Hornberger LK, Copel JA, Sklansky MS, Abuhamad A, et al. Diagnosis and treatment of fetal cardiac disease: a scientific statement from the American Heart Association. Circulation. 2014;129(21):2183-2242.
Evans N. Diagnosis of patent ductus arteriosus in the preterm newborn. Arch Dis Child Fetal Neonatal Ed. 2015;100(1)
Yildirim M, Seymen HO, Eroglu AG, Saltik L. Diagnostic accuracy of echocardiography in detecting congenital heart disease in neonates. J Pediatr. 2018;193:156-161.
Baumgartner H, Bonhoeffer P, De Groot NM, de Haan F, Deanfield JE, Galie N, et al. ESC Guidelines for managing grown-up congenital heart disease (new version 2010). Eur Heart J. 2010;31(23):2915-2957.
Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton JD, et al. De novo mutations in histone-modifying genes in congenital heart disease. Nature.
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