FREQUENCY OF SOLITARY RECTAL ULCER SYNDROME AMONG PATIENTS PRESENTING WITH BLEEDING PER RECTUM AT A TERTIARY CARE HOSPITAL

Authors

  • UK SHERWANI Department of Gastroenterology, Multan Medical and Dental College/Ibn-E-Siena Hospital Multan, Pakistan
  • S AZMAT Department of Gastroenterology, Nishtar Hospital Multan, Pakistan, Pakistan
  • M EJAZ Hepatitis Clinic, THQ Hospital, Shuja Abad, Pakistan
  • M IBRAHIM Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan
  • S SAFDAR HRI Research Center, Nishtar Medical University, Multan, Pakistan
  • R KOUSAR Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.477

Keywords:

Rectal Bleeding, Solitary Rectal Ulcer Syndrome,, Ulcer, Inflammation

Abstract

Solitary rectal ulcer syndrome is a multifaceted condition influenced by several clinical, histological, and endoscopic features. Treating this condition, especially in cases of relapse or non-responsiveness, requires a methodical and logical approach. This study aimed to determine the frequency of solitary rectal ulcer syndrome among patients presenting with rectal bleeding at a tertiary care hospital. This descriptive, cross-sectional study was conducted at the Department of Gastroenterology, Ibn-e-Sina Hospital/Multan Medical and Dental College, Multan, from 10-06-2022 to 10-06-2023. A total of 369 patients with rectal bleeding were registered in the study. Baseline investigations, including histopathology, were conducted to diagnose solitary rectal ulcer syndrome. Of the 369 registered patients, 237 (64.2%) were male, and 132 (35.8%) were female, with a mean age of 52.16 ± 9.05 years. Of these, 253 (68.6%) were from rural areas, and 116 (31.4%) were from urban areas. In 224 (60.7%), poor socioeconomic status was noted, while 145 (39.3%) had a middle-income level. Diabetes was present in 97 (26.3%), and hypertension in 134 (36.3%). The mean body mass index was 25.23 ± 1.57 kg/m2, and obesity was present in 56 (15.2%) patients. Solitary rectal ulcer syndrome was observed in 25 (6.8%) patients. The study concluded that there is a high frequency of Solitary rectal ulcer syndrome (SRUS) among patients presenting with rectal bleeding. Solitary rectal ulcer syndrome (SRUS) was significantly associated with increasing age, socioeconomic status, diabetes, hypertension, and obesity. All clinicians treating such patients should anticipate Solitary rectal ulcer syndrome (SRUS) for early diagnosis and proper management, which will improve their prognosis and quality of life.

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References

Abdi, S., Tavakolikia, N., Yamini, M., Bagheri, M., Sadeghi, A., Pourhoseingholi, M. A., Shahrokh, S., and Pasha, M. A. (2019). Solitary rectal ulcer syndrome: addition of rectal therapies to biofeedback is more effective than biofeedback alone. Gastroenterology and Hepatology From bed to Bench 12, 197.

Abdullah, M. S., Khan, M. Y., Abdullah, M. S., Atiq-ur-Rehman, S., and Ali, S. (2017). Different clinical presentations of patients with colorectal cancer visiting Bahawal Victoria Hospital, Bahawalpur. Pak J Surg 33, 59-63.

Abusharifah, O., Bokhary, R. Y., Mosli, M. H., and Saadah, O. I. (2021). Solitary rectal ulcer syndrome in children and adolescents: a descriptive clinicopathologic study. International Journal of Clinical and Experimental Pathology 14, 399.

AlGhulayqah, A. I., Abu-Farhaneh, E. H., AlSohaibani, F. I., Almadi, M. A., and AlMana, H. M. (2016). Solitary rectal ulcer syndrome: A single-center case series. Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association 22, 456.

Bardou, M., Barkun, A. N., and Martel, M. (2013). Obesity and colorectal cancer. Gut 62, 933-947.

Ejaz, Z., Khan, S. U., Rehman, R. U., Jibran, M. S., Khan, S. U., and Rehman, R. (2023). Solitary rectal ulcer syndrome in patients presenting with lower gastrointestinal bleeding: a tertiary-care hospital experience. Cureus 15.

Forootan, M., Shekarchizadeh, M., Farmanara, H., Esfahani, A. R. S., and Esfahani, M. S. (2018). Biofeedback efficacy to improve clinical symptoms and endoscopic signs of solitary rectal ulcer syndrome. European Journal of Translational Myology 28.

Gouriou, C., Chambaz, M., Ropert, A., Bouguen, G., Desfourneaux, V., Siproudhis, L., and Brochard, C. (2018). A systematic literature review on solitary rectal ulcer syndrome: is there a therapeutic consensus in 2018? International Journal of Colorectal Disease 33, 1647-1655.

Jha, A. K., Purkayastha, S., and Dayal, V. M. (2021). Endoscopic Mucosectomy: A Novel Technique for Management of Polypoidal Solitary Rectal Ulcer Syndrome. ACG Case Reports Journal 8.

MUBASHIR, A., BHATTI, A., CHAUDURY, T., KHURSHEED, K., ZAIDI, N., SHAMIN, A., KHAN, S., and SARWAR, G. (1997). Colorectal Carcinoma An Analytical Study of 104 Cases. Annals of King Edward Medical University 3, 14-16.

Muhammad, S. D., Faisal, M. S., and Mian, A. S. The Diagnostic Yield of Colonoscopy Among 114 Patients Presenting with Bleeding Per Rectum for Early Detection of.

Rao, S. S., Ozturk, R., De Ocampo, S., and Stessman, M. (2006). Pathophysiology and role of biofeedback therapy in solitary rectal ulcer syndrome. Vol. 101, pp. 613-618. LWW.

Shah, A., Bohra, S., and Desai, S. (2021). Argon plasma coagulation—an effective treatment for solitary rectal ulcer syndrome: A single-center experience from western India. Indian Journal of Gastroenterology 40, 35-40.

Shah, M. F., Ali, I. S., and Faraz, A. (2016). COLORECTAL CANCER: SITE DISTRIBUTION. The Professional Medical Journal 23, 687-692.

Soomro, S. H., Baloch, I., Shaikh, S. A., Bhatti, N., and Shaikh, B. (2011). Colorectal carcinoma: our experience at tertiary care hospital. Rawal Med J 36, 202-205.

Zia, N., Hussain, T., Salamat, A., Mirza, S., Hassan, F., and Waqar, A. (2008). Diagnostic evaluation of patients presenting with bleeding per rectum by colonoscopy. J Ayub Med Coll Abbottabad 20, 73-6.

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Published

2023-10-17

How to Cite

SHERWANI, U., AZMAT, S., EJAZ, M., IBRAHIM , M., SAFDAR, S., & KOUSAR, R. (2023). FREQUENCY OF SOLITARY RECTAL ULCER SYNDROME AMONG PATIENTS PRESENTING WITH BLEEDING PER RECTUM AT A TERTIARY CARE HOSPITAL. Biological and Clinical Sciences Research Journal, 2023(1), 477. https://doi.org/10.54112/bcsrj.v2023i1.477

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