FACTORS LEADING TO TRANSIENT TACHYPNEA OF NEWBORN (TTN) IN BABIES, DELIVERED BY SPONTANEOUS VAGINAL DELIVERY AT TERTIARY CARE HOSPITAL KARACHI

Authors

  • M EJAZ Department of Paediatrics, Ziauddin University, and Hospital Karachi, Pakistan
  • F ZAFAR Department of Paediatrics, Ziauddin University, and Hospital Karachi, Pakistan
  • M IQBAL Department of Paediatrics, Ziauddin University, and Hospital Karachi, Pakistan
  • L KHAN Department of Paediatrics, Ziauddin University, and Hospital Karachi, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.498

Keywords:

Transient Tachypnea Of Newborn, Maternal Diabetes, Obesity, PROM, Low APGAR Score.

Abstract

Neonatal respiratory distress is a common issue, and one of its types is Transient Tachypnea of the Newborn (TTN), which happens when leftover lung fluid is not removed from the body on time. TTN usually occurs within the first 24 to 72 hours after delivery. This study aims to determine the frequency of TTN in newborns delivered vaginally and spontaneously at a tertiary care hospital in Karachi and identify the factors that may contribute to the condition. The study adopted a cross-sectional design and was conducted in the Neonatal Intensive Care Unit of the Department of Pediatric Medicine, Ziauddin Hospital, Karachi. After obtaining the necessary approvals, the study lasted for 9 months, from December 2021 to September 2022. Both quantitative and qualitative data were collected, assembled, and analyzed. Stratification was employed to adjust for effect modifiers, and a chi-square test was used to test for statistical significance with a p-value of 0.05. The study included 153 patients who met the inclusion and exclusion criteria. The average gestational age, height, weight, OFC, length of hospital stay, and mother's age were 30.7 ± 4.3 weeks, 49 ± 1.79 cm, 3.01 ± 0.38 kg, 36.65 ± 1.08 cm, 3.92 ± 4.65 days, and 39.8 ± 2.78 weeks, respectively. Of the 153 patients, 71 (46.4%) were male and 82 (53.6%) were female. 44.4%, 31.4%, 45.1%, and 31.4% of the patients had maternal diabetes, PROM, obesity, and low APGAR scores, respectively. The study found maternal diabetes and obesity were the primary risk factors for TTN in newborns. The study emphasizes the importance of good antenatal and obstetric care to detect any early problems during pregnancy that may contribute to the incidence of TTN.

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References

Ahmed, M. R., Sayed Ahmed, W. A., and Mohammed, T. Y. (2015). Antenatal steroids at 37 weeks, does it reduce neonatal respiratory morbidity? A randomized trial. The Journal of Maternal-Fetal & Neonatal Medicine 28, 1486-1490.

Al-Lawama, M., AlZaatreh, A., Elrajabi, R., Abdelhamid, S., and Badran, E. (2019). Prolonged rupture of membranes, neonatal outcomes and management guidelines. Journal of clinical medicine research 11, 360.

Bahadue, F. L., and Soll, R. (2012). Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome. Cochrane Database of Systematic Reviews.

Bak, S. Y., Shin, Y. H., Jeon, J. H., Park, K. H., Kang, J. H., Cha, D. H., Han, M. Y., Jo, H. S., Lee, K. H., and Lee, C. A. (2012). Prognostic factors for treatment outcomes in transient tachypnea of the newborn. Pediatrics International 54, 875-880.

Carlo, W. A., McDonald, S. A., Fanaroff, A. A., Vohr, B. R., Stoll, B. J., Ehrenkranz, R. A., Andrews, W. W., Wallace, D., Das, A., and Bell, E. F. (2011). Association of antenatal corticosteroids with mortality and neurodevelopmental outcomes among infants born at 22 to 25 weeks' gestation. Jama 306, 2348-2358.

DERNEĞİ, T. N. TERM YENİDOĞANDA SOLUNUM SIKINTISI TANI, TEDAVİ VE KORUNMA REHBERİ.

Gallacher, D. J., Hart, K., and Kotecha, S. (2016). Common respiratory conditions of the newborn. Breathe 12, 30-42.

Gülmezoglu, A. M., Crowther, C. A., Middleton, P., and Heatley, E. (2012). Induction of labour for improving birth outcomes for women at or beyond term. Cochrane database of systematic reviews.

Hibbard, J. U., Wilkins, I., Sun, L., Gregory, K., Haberman, S., Hoffman, M., Kominiarek, M. A., Reddy, U., Bailit, J., and Branch, D. W. (2010). Respiratory morbidity in late preterm births. JAMA: the journal of the American Medical Association 304, 419.

Jobe, A. H. (2012). Effects of chorioamnionitis on the fetal lung. Clinics in perinatology 39, 441-457.

Kolås, T., Saugstad, O. D., Daltveit, A. K., Nilsen, S. T., and Øian, P. (2006). Planned cesarean versus planned vaginal delivery at term: comparison of newborn infant outcomes. American journal of obstetrics and gynecology 195, 1538-1543.

Kotecha, S. J., Gallacher, D. J., and Kotecha, S. (2016). The respiratory consequences of early-term birth and delivery by caesarean sections. Paediatric respiratory reviews 19, 49-55.

Oztekın, O., Kalay, S., Tayman, C., Namuslu, M., and Celık, H. T. (2014). Levels of ischemia-modified albumin in transient tachypnea of the newborn. American journal of perinatology, 193-198.

Pramanik, A. K., Rangaswamy, N., and Gates, T. (2015). Neonatal respiratory distress: a practical approach to its diagnosis and management. Pediatric Clinics 62, 453-469.

Reuter, S., Moser, C., and Baack, M. (2014). Respiratory distress in the newborn. Pediatrics in review 35, 417-429.

Takaya, A., Igarashi, M., Nakajima, M., Miyake, H., Shima, Y., and Suzuki, S. (2008). Risk factors for transient tachypnea of the newborn in infants delivered vaginally at 37 weeks or later. Journal of Nippon Medical School 75, 269-273.

Verani, J. R., McGee, L., and Schrag, S. J. (2010). Prevention of perinatal group B streptococcal disease: revised guidelines from CDC, 2010. Department of Health and Human Services, Centers for Disease Control and ….

Warren, J. B., and Anderson, J. M. (2010). Newborn respiratory disorders. Pediatrics in review 31, 487-496.

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Published

2023-10-27

How to Cite

EJAZ , M., ZAFAR , F., IQBAL , M., & KHAN , L. (2023). FACTORS LEADING TO TRANSIENT TACHYPNEA OF NEWBORN (TTN) IN BABIES, DELIVERED BY SPONTANEOUS VAGINAL DELIVERY AT TERTIARY CARE HOSPITAL KARACHI. Biological and Clinical Sciences Research Journal, 2023(1), 498. https://doi.org/10.54112/bcsrj.v2023i1.498

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