COMPARISON OF NON-INVASIVE FOLLOW-UP TESTING IN PATIENTS AFTER PERCUTANEOUS CORONARY INTERVENTION WITH DRUG-ELUTING STENT IMPLANTATION

Authors

  • L AJMAL Department of Cardiology, Khyber Teaching Hospital MTI Peshawar, Pakistan
  • AA KHAN Department of Cardiology, Wapda Hospital Peshawar, Pakistan
  • MA AJMAL Department of Cardiology, Wapda Hospital Peshawar, Pakistan
  • H ULLAH Department of Cardiology, Lady Reading Hospital Peshawar, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.436

Keywords:

Percutaneous Coronary Intervention, Coronary Artery Disease, Drug-Eluting Stent, Restenosis, Stent Thrombosis, Non-Invasive, Diagnostic Accuracy, Prognostic Value, Cost-Effectiveness

Abstract

Percutaneous coronary intervention (PCI) is a common procedure used to treat obstructive coronary artery disease (CAD). The aim of this retrospective cohort study, conducted at the Armed Forces Institute of Cardiology from January 2019 to December 2021, was to compare non-invasive follow-up testing in patients who underwent PCI with drug-eluting stent (DES) implantation. The study included 210 patients who underwent PCI with DES implantation at AFIC during the specified period. Researchers extracted patient data, including demographic information, clinical characteristics, PCI procedural details, and baseline comorbidities from electronic medical records. They also recorded additional data on the type of DES used, lesion characteristics, and stent dimensions. Of the 210 patients included in the study, the mean age was 62 years, with a range of 45 to 78 years. The data comprised 65% males and 35% females. The most common comorbidities were hypertension (80%), diabetes mellitus (60%), and dyslipidemia (45%). 30% of patients had a family history of coronary artery disease. During the follow-up period, restenosis was detected in 18% of patients, while stent thrombosis occurred in 7% of cases. The incidence of major adverse cardiac events (MACE) was 25%, with myocardial infarction accounting for 12%, target lesion revascularization for 10%, and cardiac mortality for 3% of MACE cases. Based on the results, the study highlights the importance of non-invasive follow-up testing in patients who have undergone PCI with DES implantation. These modalities provide diagnostic accuracy, prognostic value, and cost-effectiveness, contributing to a more comprehensive understanding of their role in post-PCI care.

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References

Alexandrescu, D.-M., Mitu, O., Costache, I. I., Macovei, L., Mitu, I., Alexandrescu, A., and Arsenescu Georgescu, C. (2021). Risk factors associated with intra‑stent restenosis after percutaneous coronary intervention. Experimental and Therapeutic Medicine 22, 1-7.

Chung, M. S., Yang, D. H., Kim, Y.-H., Roh, J.-H., Song, J., Kang, J.-W., Ahn, J.-M., Park, D.-W., Kang, S.-J., and Lee, S.-W. (2016). Stent fracture and longitudinal compression detected on coronary CT angiography in the first-and new-generation drug-eluting stents. The International Journal of Cardiovascular Imaging 32, 637-646.

Fihn, S. D., Gardin, J. M., Abrams, J., Berra, K., Blankenship, J. C., Dallas, A. P., Douglas, P. S., Foody, J. M., Gerber, T. C., and Hinderliter, A. L. (2012). 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation 126, e354-e471.

Knuuti, J., Ballo, H., Juarez-Orozco, L. E., Saraste, A., Kolh, P., Rutjes, A. W. S., Jüni, P., Windecker, S., Bax, J. J., and Wijns, W. (2018). The performance of non-invasive tests to rule-in and rule-out significant coronary artery stenosis in patients with stable angina: a meta-analysis focused on post-test disease probability. European heart journal 39, 3322-3330.

McKee, S. A., Applegate, R. J., Hoyle, J. R., Sacrinty, M. T., Kutcher, M. A., and Sane, D. C. (2007). Cocaine use is associated with an increased risk of stent thrombosis after percutaneous coronary intervention. American heart journal 154, 159-164.

Mitra, R., and Reiter, J. P. (2016). A comparison of two methods of estimating propensity scores after multiple imputation. Statistical methods in medical research 25, 188-204.

Montone, R. A., Niccoli, G., Vergni, F., Vetrugno, V., Russo, M., Mangiacapra, F., Fracassi, F., Porto, I., Leone, A. M., and Burzotta, F. (2018). Endothelial dysfunction as predictor of angina recurrence after successful percutaneous coronary intervention using second generation drug eluting stents. European Journal of Preventive Cardiology 25, 1360-1370.

Nakachi, T., Kato, S., Saito, N., Fukui, K., Iwasawa, T., Endo, T., Kosuge, M., Utsunomiya, D., Kimura, K., and Tamura, K. (2021). Non-Invasive Evaluation of Patients Undergoing Percutaneous Coronary Intervention for Chronic Total Occlusion. Journal of Clinical Medicine 10, 4712.

Nakai, M., Iwanaga, Y., Sumita, Y., Kanaoka, K., Kawakami, R., Ishii, M., Uchida, K., Nagano, N., Nakayama, T., and Nishimura, K. (2021). Validation of acute myocardial infarction and heart failure diagnoses in hospitalized patients with the nationwide claim-based JROAD-DPC database. Circulation Reports 3, 131-136.

Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., and Head, S. J. (2019). 2018 ESC/EACTS Guidelines on myocardial revascularization. European heart journal 40, 87-165.

Seki, T., Takeuchi, M., and Kawakami, K. (2022). Comparison of noninvasive follow-up testing in patients after percutaneous coronary intervention with drug-eluting stent implantation. Journal of Cardiology 80, 275-282.

Yamana, H., Moriwaki, M., Horiguchi, H., Kodan, M., Fushimi, K., and Yasunaga, H. (2017). Validity of diagnoses, procedures, and laboratory data in Japanese administrative data. Journal of Epidemiology 27, 476-482.

Yoon, Y.-H., Ahn, J.-M., Kang, D.-Y., Park, H., Cho, S.-C., Lee, P. H., Hur, S.-H., Kim, W.-J., Park, C. S., and Lee, B.-K. (2020). Pragmatic trial comparing routine versus no routine functional testing in high-risk patients who underwent percutaneous coronary intervention: rationale and design of POST-PCI trial. American heart journal 224, 156-165.

Zimmermann, F. M., Ferrara, A., Johnson, N. P., Van Nunen, L. X., Escaned, J., Albertsson, P., Erbel, R., Legrand, V., Gwon, H.-C., and Remkes, W. S. (2015). Deferral vs. performance of percutaneous coronary intervention of functionally non-significant coronary stenosis: 15-year follow-up of the DEFER trial. European heart journal 36, 3182-3188.

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Published

2023-10-03

How to Cite

AJMAL , L., KHAN , A., AJMAL , M., & ULLAH , H. (2023). COMPARISON OF NON-INVASIVE FOLLOW-UP TESTING IN PATIENTS AFTER PERCUTANEOUS CORONARY INTERVENTION WITH DRUG-ELUTING STENT IMPLANTATION. Biological and Clinical Sciences Research Journal, 2023(1), 436. https://doi.org/10.54112/bcsrj.v2023i1.436

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