ABO AND RHESUS BLOOD GROUP DISTRIBUTION IN URBAN AREA OF SOUTHERN PUNJAB MULTAN PAKISTAN

AM Bhutta; Z Tasawar; M Sajid; S Hayat; A Ali; A Malik

doi:10.54112/bcsrj.v2020i1.39

Authors

AM Bhutta Institute of Pure and Applied Biology, Bahauddin Zakariya University, Multan, Pakistan
Z Tasawar Institute of Pure and Applied Biology, Bahauddin Zakariya University, Multan, Pakistan
M Sajid Institute of Pure and Applied Biology, Bahauddin Zakariya University, Multan, Pakistan
S Hayat Institute of Molecular Biology & Biotechnology, University of Lahore, Lahore, Pakistan
A Ali Institute of Molecular Biology & Biotechnology, University of Lahore, Lahore, Pakistan
A Malik Institute of Molecular Biology & Biotechnology, University of Lahore, Lahore, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2020i1.39

Keywords:

rhesus, ABO blood group, antigens, dominance, genetic drift, correlation

Abstract

This study was conducted to find out the distribution of ABO phenotypes frequencies in urban area of Southern Punjab Multan Pakistan. A total of 1087 subjects (both male & female) were taken and their blood samples were tested for ABO blood group & Rh. by using anti sera of ABO blood grouping i.e. Anti-D, Anti-A and Anti-B, and confirmed by standard technique. Doubtful results were checked by tube method. The data was analyzed by applying Pearson correlation and chi square test. In the present study overall prevalence of blood group & Rh. positive was 997/1087 (91.72%) as compared to 90/1087 (8.28%) blood group & Rh. negative (P< 0.05). It is a part of evolution with a natural and random genetic drift selection. ABO blood group types were equally distributed but there was no significant difference in both sexes. However, among ABO blood group & Rh positive; dominance frequency was ‘B’ positive with 373 (34.32%) followed by ‘O’ positive 293 (26.95%), ‘A’ positive 218 (20.06%) and ‘AB’ positive with frequency of 113 (10.40%) respectively, and among ABO blood group & Rh. negative; ‘O’ negative was more prevalent with 42 (3.86%) followed by ‘B’ negative 23 (2.12%), ‘A’ negative 22 (2.02%), and ‘AB’ negative with frequency of 03 (0.28%) respectively In the present study ABO blood group ‘B’ positive was dominant as compared to other ABO blood groups & Rh positive (P> 0.05). Analysis of the data collected in the present study indicated that there was a dominant frequency of ABO blood group & Rh. positive as compared to Rh. negative, and blood group ‘B’ positive was dominant as compared to other ABO blood group types. The determination of the frequency of ABO blood group types in urban area Southern Punjab Multan would help us in understanding the distribution of ABO phenotypes. Whereas, the differences of ABO blood group’s frequencies in different races and regions is a part of evolution with a natural and random genetic drift selection.

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References

Babar, M., Hassan, H. S., Habib-ullah and Hassan, M. K. (1999). ABO and Rhesus Blood Group Distribution in Disrict Nowshera. Journal of Postgraduate Medical Institute, 13, 02.

Carol, R. E. and Melvin, E. (1973). “Blood type B is completely absent in most North and South American Indians “. Anthropology., (http://books.google.com/?id=fvp FAAAAMAAJ).

Daean (2005). Blood Type A: Central and Europe. 2.1. 4, (http://www.ncbi.nlm.nih.gov/books/NBK2264/#ch2.1.4Ch.).

Datta, U. K., Mondal, S. and Mukhrjee, S. (1997). A study of the distribution of ABO and Rh. (D) blood groups among Lodha- Tribe in Midnapore District of West Bengal. Journal of Indian Medical Association 95, 497-99.

Garratty, G. (2005). Relationship of blood groups to disease: do blood groups antigens have a biological role? Revista Médica del Instituto Mexicano del Seguro Social, 43: 113-21.

Ilyas, M., Iftikhar, M. and Usman, R. (2013). Frequency of ABO and Rh Blood groups in Gujranwala (Punjab), Pakistan. Biologia 59, 107-14.

Khan, B. H., Attaullah, S., and Khan, A. H. (2017). Frequency of ABO and RH (D) blood groups involving volunteer donors in District Nowshera. Journal of Postgraduate Medical Institute 31, 135-37.

Khan, M. R. (1988). Biochemistry text book. Carvan Press Darbar Market, Lahore 1988: 58

Land-stainer, K. and Wiener, A. S. (1940). An agglutinable factor in human blood recognized by immune sera for rhesus blood. Proceedings of the Society for Experimental Biology and Medicine 43, 22.

Mabood, N., Mohammad, W. and Banuri, F. (1993). Frequency of ABO and Rh (D) blood groups in Mardan. Journal of Ayub Medical Collage 6, 18.

Moslem, U. M. and Shashi, A. (1989). Haemoglobin levels and blood groups in person living at high altitude. Annals of Saudi Medicine 9, 458.

Naeem, M., Malik, A., Ali, Q., Khalid, M., Masud, S. and Bhutta, A.M., (2020a). Hepatitis B and C prevalence and its associated risk factors among school going children in urban and rural areas of District Muzaffar Garh, Pakistan. Genetics and Molecular Research 19(1). gmr16039975

Naeem, M., Hassan, S., Masud, S., Ali, Q., Naeem, A.D. and Naeem, Z., (2020b). Comparative analysis of genomic DNA extraction protocols: Maxi-preparation of quality DNA for genetic evaluation and phylogenetic studies. Genetics and Molecular Research 19(1), gmr16039976.

Pinkston, J. A. and Cole, P. (1996). ABO blood groups and salivary gland tumor. Cancer Causes Control 6, 572.

Qureshi, M. A. and Bhatti, R. (2003). Frequency of ABO blood groups among the Diabetes Mellitus type 2 patients. Journal of the College of Physicians and Surgeons Pakistan 13, 453-55.

Shah, S. H., Subhani, F., Haqh, and Aslam, M. J. (1990). Frequency of ABO and Rh (D) blood groups in Lahore. Journal of Science and Technology 14, 107-9.

Umer, K. M., Waqas, B. M., Rehman, R. and Rizwan, A. K. (2014). Frequency of ABO and Rh (D) Blood groups among blood donors in Lahore, Pakistan. International Journal of Advanced Biological and Biomedical Research 2, 597-600.

Umit, T., Tiftik, E. N., Sakir, U., Ozrur, G., Tamer, I. K. and Handan, C. (2008). Relationship between ABO blood group and skin. Dermatology Online Journal 11, 1-6.

Wikipedia, (2017). ABO Blood type distribution by country- Available at: http://en.wikipedia . org/wiki/Blood_type_distribution_by_country.Wikimedia Foundation, Inc.,

Zhang, Bai-Lin., Na-He., Yu-Bei, H., Feng-Ju, S. and Ke-Xin, C. (2014). ABO Blood Groups and Risk of Cancer: a Systematic Review and Meta-analysis. Asian Pacific Journal of Cancer Prevention 15, 4643-50