EFFICACY OF DOPPLER ULTRASOUND IN DETECTING MALIGNANT PALPABLE THYROID NODULES

MA SHAHZAD; S MUSHTAQ; A ALI; SM BILAL

doi:10.54112/bcsrj.v2023i1.391

Authors

MA SHAHZAD Department of Radiologist, Nishter Medical University and Hospital (NMU & H) Multan, Pakistan
S MUSHTAQ Department of Radiologist, Nishter Medical University and Hospital (NMU & H) Multan, Pakistan
A ALI Department of Radiologist, Nishter Medical University and Hospital (NMU & H) Multan, Pakistan
SM BILAL Department of Radiologist, Nishter Medical University and Hospital (NMU & H) Multan, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.391

Keywords:

Doppler ultrasound, Histopathology, Malignancy, Palpable thyroid nodules

Abstract

This study aimed to assess the efficacy of Doppler Ultrasound in detecting malignant palpable thyroid nodules. A Cross-sectional, descriptive study was conducted in the Department of Radiology, Nishtar Medical College and Hospital, Multan, from January 2022 to December 2022. A total of 196 patients with palpable thyroid nodules were included in the study. Doppler ultrasound was performed on all patients. Samples were sent for histopathology to the same laboratory whose pathologist was blinded to ultrasound results. On histopathology, 37 patients (18.9%) showed malignancy, and 159 (81.1%) showed no malignant nodules. On Doppler ultrasound, 36 (18.37%) patients were positive for malignancy, and 160(81.63%) showed no malignancy. Doppler ultrasound showed excellent sensitivity (86.4%), specificity (97.4%), positive predictive value (88.9%), negative predictive value (96.8%), and diagnostic accuracy (95.4%). Doppler ultrasound has a higher diagnostic accuracy for palpable thyroid nodules than histopathology.

Downloads

Download data is not yet available.

References

Ahn, H. S., Lee, J. B., Seo, M., Park, S. H., and Choi, B. I. (2018). Distinguishing benign from malignant thyroid nodules using thyroid ultrasonography: utility of adding superb microvascular imaging and elastography. La radiologia medica 123, 260-270.

Al Mamun, A., Alam, Z., Islam, M., Mahamud, M., Rahman, M., and Aich, M. L. (2018). Study of pathological variations of solitary thyroid nodule. Bangladesh Journal of Otorhinolaryngology 24, 105-114.

Aslan, A., Sancak, S., Aslan, M., Ayaz, E., Inan, I., Ozkanli, S., Alimoğlu, O., and Yıkılmaz, A. (2018). Diagnostic value of duplex Doppler ultrasound parameters in papillary thyroid carcinoma. Acta Endocrinologica (Bucharest) 14, 43.

Chambara, N., and Ying, M. (2019). The diagnostic efficiency of ultrasound computer–aided diagnosis in differentiating thyroid nodules: A systematic review and narrative synthesis. Cancers 11, 1759.

Chung, J., Lee, Y. J., Choi, Y. J., Ha, E. J., Suh, C. H., Choi, M., Baek, J. H., Na, D. G., of Radiology, K. S., and Radiology, K. S. o. T. (2020). Clinical applications of Doppler ultrasonography for thyroid disease: consensus statement by the Korean Society of Thyroid Radiology. Ultrasonography 39, 315.

Du, Y.-R., Ji, C.-L., Wu, Y., and Gu, X.-G. (2018). Combination of ultrasound elastography with TI-RADS in the diagnosis of small thyroid nodules (≤ 10 mm): A new method to increase the diagnostic performance. European journal of radiology 109, 33-40.

Durante, C., Grani, G., Lamartina, L., Filetti, S., Mandel, S. J., and Cooper, D. S. (2018). The diagnosis and management of thyroid nodules: a review. Jama 319, 914-924.

Ishtiaq, S., Arshad, N., Ali, A., and John, A. (2022). Role of Ultrasound and Color Doppler in Assessment of Thyroid Nodules: Ultrasound and colour doppler for thyroid nodules. Pakistan BioMedical Journal, 51-54.

Kalantari, S. (2018). The diagnostic value of color Doppler ultrasonography in predicting thyroid nodules malignancy. The international tinnitus journal 22, 35-39.

Koh, J., Lee, E., Han, K., Kim, E.-K., Son, E. J., Sohn, Y.-M., Seo, M., Kwon, M.-r., Yoon, J. H., and Lee, J. H. (2020). Diagnosis of thyroid nodules on ultrasonography by a deep convolutional neural network. Scientific reports 10, 15245.

Maddaloni, E., Briganti, S. I., Crescenzi, A., Anguissola, G. B., Perrella, E., Taffon, C., Palermo, A., Manfrini, S., Pozzilli, P., and Pantano, A. L. (2021). Usefulness of color Doppler ultrasonography in the risk stratification of thyroid nodules. European thyroid journal 10, 339-344.

Nawaz, S., Khan, M. B., Parveen, B., Asif, M., Rashid, M., Azeem, M., and Nawaz, M. (2018). Diagnostic accuracy of thyroid ultrasound in detection of malignancy in thyroid nodules. Pakistan Journal of Physiology 14, 11-13.

Radzina, M., Ratniece, M., Putrins, D. S., Saule, L., and Cantisani, V. (2021). Performance of contrast-enhanced ultrasound in thyroid nodules: review of current state and future perspectives. Cancers 13, 5469.

Sahu, N., and Padhy, R. N. (2018). Bayesian analysis of high-resolution ultrasonography and guided fine needle aspiration cytology in diagnosis of palpable thyroid nodules. Brazilian Journal of Otorhinolaryngology 84, 20-27.

Zhan, J., and Ding, H. (2018). Application of contrast-enhanced ultrasound for evaluation of thyroid nodules. Ultrasonography 37, 288.