A Comparative Study on Duration of Supraclavicular Plexus Block Using Dexamethasone vs Tramadol as an Adjuvant to Bupivacaine for Arm and Forearm Surgeries
DOI:
https://doi.org/10.54112/bcsrj.v6i5.2217Keywords:
Brachial plexus block, dexamethasone, tramadol, bupivacaine, supraclavicular block, postoperative analgesiaAbstract
Supraclavicular brachial plexus block is widely used for upper limb surgeries due to its rapid onset and reliable anesthesia. However, the limited duration of analgesia with local anesthetics necessitates the use of adjuvants. Dexamethasone and tramadol are commonly used agents, but comparative evidence in the Pakistani population remains limited. Objective: To compare the effects of dexamethasone versus tramadol as adjuvants to bupivacaine on the duration of supraclavicular brachial plexus block in patients undergoing arm and forearm surgeries. Methods: This comparative study was conducted at the Department of Anesthesia, Aziz Bhatti Shaheed Teaching Hospital, Gujrat, from April 2024 to March 2025. A total of 70 patients (ASA I–II), aged 18–60 years, were assigned to two groups. Group A received bupivacaine with dexamethasone (8 mg), while Group B received bupivacaine with tramadol (100 mg). Primary outcomes included onset and duration of sensory and motor block, and duration of analgesia. Secondary outcomes included pain scores (VAS), rescue analgesic requirement, and adverse effects. Data were analyzed using SPSS version 26, with p ≤ 0.05 considered statistically significant. Results: The mean age of participants was 38.9 ± 11.6 years, with a predominance of males. Baseline characteristics were comparable between groups. Dexamethasone demonstrated significantly faster onset of sensory (11.2 ± 2.4 vs 13.1 ± 2.8 minutes, p=0.003) and motor block (15.6 ± 3.1 vs 17.9 ± 3.5 minutes, p=0.005). It also significantly prolonged sensory block (812.4 ± 108.6 vs 641.8 ± 96.3 minutes), motor block (694.2 ± 101.7 vs 548.9 ± 88.4 minutes), and duration of analgesia (928.6 ± 121.4 vs 716.5 ± 104.9 minutes) (p<0.001 for all). Pain scores were significantly lower in the dexamethasone group at 6, 12, and 24 hours. Fewer patients required early rescue analgesia (22.9% vs 60.0%, p=0.002), and total analgesic consumption was reduced. Hemodynamic parameters were comparable, while nausea and vomiting were more frequent in the tramadol group. Conclusion: Dexamethasone is superior to tramadol as an adjuvant to bupivacaine in supraclavicular brachial plexus block, providing faster onset, prolonged analgesia, improved pain control, and fewer adverse effects.
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1. Nagar K. Comparative study between tramadol and dexamethasone as an adjuvant to bupivacaine in supraclavicular brachial plexus block. Indian J Clin Anaesth. 2023;10(1):21-25. https://doi.org/10.18231/j.ijca.2023.004 DOI: https://doi.org/10.18231/j.ijca.2023.004
2. Islam MR, Yesmin L, Rahman MP, Khan ABMSA, Hossain MM, Rahman MM, et al. Effect of dexamethasone on the duration of analgesia for supraclavicular brachial plexus block. KYAMC J. 2021;11(4):199-203. https://doi.org/10.3329/kyamcj.v11i4.51997 DOI: https://doi.org/10.3329/kyamcj.v11i4.51997
3. Pandey RP, Chandra R. A comparative evaluation of dexamethasone and tramadol as adjuvants to levobupivacaine in supraclavicular block. Acad Anesthesiol Int. 2020;5(1):100-102. https://doi.org/10.21276/aan.2020.5.1.20 DOI: https://doi.org/10.21276/aan.2020.5.1.20
4. Kamble NP, Gajbhare MN, Pimparkar PR, Gaikwad MR. Comparative study of tramadol and nalbuphine as an adjuvant to ropivacaine in supraclavicular block: a cross-sectional observational study. Indian J Clin Anaesth. 2024;11(2):132-139. DOI: https://doi.org/10.18231/j.ijca.2024.029
5. Mughal N, Shah A, Latif S, Naseem U, Naz F, Awan MN. Comparison of outcomes of intravenous dexamethasone versus placebo as an adjunct to local anaesthetic brachial plexus block for upper limb surgery. J Islamabad Med Dent Coll. 2024;13(2):217-223. DOI: https://doi.org/10.35787/jimdc.v13i2.1109
6. Vaidya SR, Neupane S, Shrestha K, Ghale T. Efficacy of dexamethasone as an adjuvant to bupivacaine in supraclavicular brachial plexus block. J Gandaki Med Coll Nepal. 2022;15(1):63-68. https://doi.org/10.3126/jgmcn.v15i1.43999 DOI: https://doi.org/10.3126/jgmcn.v15i1.43999
7. Kore SS, Ubhe SB, Fasil F. Comparison between dexamethasone and fentanyl as an adjuvant to bupivacaine and lignocaine in supraclavicular brachial plexus block for upper limb surgery. J Pharmacol Pharmacother. 2022;13(1):59-65. https://doi.org/10.1177/0976500X221085803 DOI: https://doi.org/10.1177/0976500X221085803
8. Marathe RM, Shende SY, Khairmode UB, Gorgile RN. Supraclavicular brachial plexus block with and without dexamethasone as an adjuvant to local anesthetics: an observational study. Indian J Clin Anaesth. 2020;7(4):645-651. DOI: https://doi.org/10.18231/j.ijca.2020.116
9. Hossain ME, Saha PL, Tusher SM, Chowdhury MNS, Biswas S, Nasrin S, et al. Magnesium sulfate versus fentanyl as an adjuvant with bupivacaine in supraclavicular brachial plexus block: a comparative study. Med Res Chron. 2021;8(6):475-489. https://doi.org/10.26838/MEDRECH.2021.8.6.565 DOI: https://doi.org/10.26838/MEDRECH.2021.8.6.565
10. Khaleeq S, Azam M, Siddiq S, Shahid A, Butt Z, Asad N. Comparison of dexmedetomidine and dexamethasone as adjuvants to bupivacaine in supraclavicular brachial plexus block. Ann Punjab Med Coll. 2020;14(2):122-125. https://doi.org/10.29054/apmc/2020.889 DOI: https://doi.org/10.29054/apmc/2020.889
11. Schubert AK, Seneviratne V, Stolz J, Wiesmann T, Wulf H, Eberhart L, et al. The effect of adjuvants added to local anaesthetics for single-injection upper extremity peripheral regional anaesthesia: a systematic review with network meta-analysis of randomised trials. Eur J Anaesthesiol. 2023;40(9):672-690. https://doi.org/10.1097/EJA.0000000000001860 DOI: https://doi.org/10.1097/EJA.0000000000001860
12. Kalagac Fabris L. Pro and contra on adjuvants to neuraxial anesthesia and peripheral nerve blocks. Acta Clin Croat. 2022;61(Suppl 2):57-66. https://doi.org/10.20471/acc.2022.61.s2.07 DOI: https://doi.org/10.20471/acc.2022.61.s2.07
13. Cherian SS, Kumar S, Jaleel J, GC B. Assessment of supraclavicular brachial plexus block with or without dexamethasone as an adjuvant to 0.5% levobupivacaine. Int J Med Anesthesiol. 2021;4(1):20-24. https://doi.org/10.33545/26643766.2021.v4.i1a.190 DOI: https://doi.org/10.33545/26643766.2021.v4.i1a.191
14. Baloda R, Rohilla K, Battu R. Comparison between dexamethasone and clonidine as an adjuvant to 0.5% levobupivacaine in supraclavicular brachial plexus block. Asian J Med Sci. 2023;14(5):41-46. https://doi.org/10.3126/ajms.v14i5.51342 DOI: https://doi.org/10.3126/ajms.v14i5.51342
15. Iqbal U, Akram M, Khan A, Qureshi A, Sheikh F. Comparison of dexamethasone and midazolam in improving the efficacy of 0.5% bupivacaine in ultrasound-guided supraclavicular brachial plexus block. Prof Med J. 2020;27(6):1176-1181. https://doi.org/10.29309/TPMJ/2020.27.06.3957 DOI: https://doi.org/10.29309/TPMJ/2020.27.06.3957
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