CORRELATION BETWEEN FINE NEEDLE ASPIRATION CYTOLOGY AND CORRESPONDING ULTRASOUND BIRADS SCORE IN MAMMARY MALIGNANCY

Authors

  • I ZAFAR Department of Pathology, IbneSina Hospital & Multan Medical & Dental College Multan, Pakistan
  • A SAMAD Department of Pathology, IbneSina Hospital & Multan Medical & Dental College Multan, Pakistan
  • A HAROON Department of Pathology, IbneSina Hospital & Multan Medical & Dental College Multan, Pakistan
  • N FAYYAZ Department of Pathology, IbneSina Hospital & Multan Medical & Dental College Multan, Pakistan
  • N FAYYAZ Department of Pathology, IbneSina Hospital & Multan Medical & Dental College Multan, Pakistan
  • N MAHMOOD Department of Hematology, Central Park Medical College Lahore, Pakistan
  • AA BUKHARI Department of Pathology, IbneSina Hospital & Multan Medical & Dental College Multan, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2022i1.130

Keywords:

Mammary malignancy, BIRADS, Fine needle aspiration cytology

Abstract

The aim of this study is to evaluate accuracy of ultrasound in diagnosing breast cancer and assessing correlation of radiological findings with findings of fine needle aspiration cytology (FNAC). Retrospective study was conducted at IbneSina Hospital& Multan Medical & Dental College Multan from July 2021 to December 2021. Study was conducted on 40 patients aged between 30 to 90 years having breast limps. Subjects underwent clinical and ultrasonic examination and BIRADS score was correlated with cytology data. Major ultrasonic finding was that irregular lesion was found in 21 (52.5%) subjects.  In 10 (25%) patientsill defined lesion was found. FNAC revealed severe atypia in 7.5% and mammary carcinoma in 92.5% cases.BIRADS score V, IV and III were assigned to 75%, 20% and 5% cases respectively.  Correlation of FNAC results with ultrasonic findings showed 90.6% accuracy of ultrasound in diagnosis of breast cancer. Ultrasonography provides accurate diagnosis of breast lesions and is recommended radiographic modality for assessing underlying cause of palpable breast mass.

Downloads

Download data is not yet available.

References

Al Alwan, N. A. (2015). Establishing national guidelines for early detection of breast cancer in Iraq: Clinical Implications and Perspectives. International Journal 3, 539-555.

Badu-Peprah, A., and Adu-Sarkodie, Y. (2018). Accuracy of clinical diagnosis, mammography and ultrasonography in preoperative assessment of breast cancer. Ghana medical journal 52, 133-139.

Chandanwale, S. S., Ravishankar, R., Garg, A. A., and Ambekar, M. R. (2022). Image-guided fine-needle aspiration cytology or core biopsy–A key to definitive diagnosis of tuberculous mastitis. International Journal of Mycobacteriology 11, 323.

CO, C. (2015). Facts & Figures 2015-2016.

Ganggayah, M. D., Taib, N. A., Har, Y. C., Lio, P., and Dhillon, S. K. (2019). Predicting factors for survival of breast cancer patients using machine learning techniques. BMC medical informatics and decision making 19, 1-17.

Lalchan, S., Thapa, M., Sharma, P., Shrestha, S., Kc, S., Pathak, M., Gyawali, M., and Tiwari, P. (2015). Role of mammography combined with ultrasonography in evaluation of breast lump. Am J Public Health Res 3, 95-8.

Machado, P., Eisenbrey, J. R., Stanczak, M., Cavanaugh, B. C., Zorn, L. M., and Forsberg, F. (2019). Characterization of breast microcalcifications using a new ultrasound image‐processing technique. Journal of Ultrasound in Medicine 38, 1733-1738.

Moazeni Bistgani, M., Basravi, M., Taheri, A., Taheri, S., and Kheiri, S. (2019). Accuracy of fine needle aspiration compared to core needle biopsy in breast masses. Journal of Shahrekord University of Medical Sciences.

Mohson, K. I. (2016). Ultrasound findings in prediction of breast cancer histological grade and HER2 status. Journal of the Faculty of Medicine Baghdad 58, 26-28.

Mubuuke, A. G. (2019). Uptake of the BI-RADS Ultrasound Characterization of Breast Masses: Perceptions among Staff at Mulago National Referral Hospital, Uganda.

Mustafa, A. A. (2014). BI-RADS 4 and 5 breast lesions: correlation between sonographic findings and histopathological results following ultrasound-guided FNAC. kufa Journal for Nursing sciences 4, 188-195.

Mutebi, M., Anderson, B. O., Duggan, C., Adebamowo, C., Agarwal, G., Ali, Z., Bird, P., Bourque, J. M., DeBoer, R., and Gebrim, L. H. (2020). Breast cancer treatment: A phased approach to implementation. Cancer 126, 2365-2378.

Niu, S., Huang, J., Li, J., Liu, X., Wang, D., Zhang, R., Wang, Y., Shen, H., Qi, M., and Xiao, Y. (2020). Application of ultrasound artificial intelligence in the differential diagnosis between benign and malignant breast lesions of BI-RADS 4A. BMC cancer 20, 1-7.

Organization, W. H. (2019). International agency for research on cancer.

Sih, B. T. (2018). EFFECTS OF CHEMOTHERAPY AND RADIOTHERAPY ON BLOOD COMPONENTS OF BREAST CANCER PATIENTS. Pakistan Journal of Biotechnology 15, 821-825.

Sood, R., Rositch, A. F., Shakoor, D., Ambinder, E., Pool, K.-L., Pollack, E., Mollura, D. J., Mullen, L. A., and Harvey, S. C. (2019). Ultrasound for breast cancer detection globally: a systematic review and meta-analysis. Journal of global oncology 5, 1-17.

Stepanek, T., Constantinou, N., Marshall, H., Pham, R., Thompson, C., Dubchuk, C., and Plecha, D. (2019). Changes in the utilization of the BI-RADS category 3 assessment in recalled patients before and after the implementation of screening digital breast tomosynthesis. Academic Radiology 26, 1515-1525.

Tricoli, J. V., and Bleyer, A. (2018). Adolescent and young adult cancer biology. The Cancer Journal 24, 267-274.

Downloads

Published

2022-11-02

How to Cite

ZAFAR, I., SAMAD, A., HAROON, A., FAYYAZ, N., FAYYAZ, N., MAHMOOD, N., & BUKHARI, A. (2022). CORRELATION BETWEEN FINE NEEDLE ASPIRATION CYTOLOGY AND CORRESPONDING ULTRASOUND BIRADS SCORE IN MAMMARY MALIGNANCY. Biological and Clinical Sciences Research Journal, 2022(1). https://doi.org/10.54112/bcsrj.v2022i1.130

Issue

Section

Original Research Articles

Most read articles by the same author(s)