ANTIOXIDANT ASSESSMENT OF SOME THERAPEUTICALLY IMPORTANT PLANTS AS ANTI-AGING AGENTS

F UROOJ; A IFTIKHAR; K MAZHAR; R ALTAF; M GONDAL; A RAFAQAT; N SHABBIR

doi:10.54112/bcsrj.v2024i1.969

Authors

F UROOJ Ecology and Evolution Laboratory, Department of Botany, University of the Punjab, Lahore, Pakistan
A IFTIKHAR Akhtar Saeed College of Pharmacy, Rawalpindi, Pakistan
K MAZHAR School of Pharmacy, University of Management and Technology Lahore, Pakistan
R ALTAF School of Pharmacy, University of Management and Technology, Lahore, Pakistan
M GONDAL Department of Pharmaceutical Chemistry, Yashfeen College of Pharmacy, Lahore, Pakistan
A RAFAQAT Yashfeen College of Pharmacy, Lahore, Pakistan
N SHABBIR Rashid Latif College of Pharmacy, Lahore, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2024i1.969

Keywords:

Antioxidants, Camellia sinensis, Cocos nucifera, Ficus carica, Oxidative stress, Skin diseases, Total Phenolic Content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH).

Abstract

Skin, the protective outer covering of the body, acts as an insulator between internal and external environments. Skin diseases are a significant concern today, primarily due to oxidative stress. Although synthetic compounds and drugs are available, they often contain toxic and carcinogenic compounds, leading to cancer. Herbal and natural products, rich in natural antioxidants, are preferred as remedies. Objective: To evaluate the antioxidant potential of different solvent extracts at various concentrations from five plants: Aloe barbadensis, Camellia sinensis, Cocos nucifera, Ficus carica, and Rosa indica, using DPPH, Total Phenolic Content (TPC), and Total Antioxidant Assay. Methods: This experimental study was conducted over six months in a laboratory setting. Various solvent extracts (100% v/v) of the five selected plants were prepared, and their antioxidant potentials were evaluated using DPPH radical scavenging assay, TPC assay, and Total Antioxidant Assay. Data were analyzed using ANOVA, and results were expressed as mean ± standard deviation (SD). Results: Among all the plant extracts, the 100% v/v Petroleum ether extract of Aloe barbadensis showed the highest radical scavenging value, i.e., 98.6±0.55. Following the evaluation through DPPH, TPC, and Total Antioxidant Assays, a combination of the five plant extracts was proposed as a potent source of natural antioxidants. Conclusion: The study concluded that the selected plant extracts, particularly the Petroleum ether extract of Aloe barbadensis, possess significant antioxidant potential. These extracts can be utilized in cosmetics and other industries as natural antioxidant sources, offering a safer alternative to synthetic compounds.

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