POST-CHOLECYSTECTOMY SYNDROME: A STUDY OF 200 CONSECUTIVE PATIENTS WITH GALL BLADDER PATHOLOGY WHO UNDERWENT LAPAROSCOPIC CHOLECYSTECTOMY
DOI:
https://doi.org/10.54112/bcsrj.v2023i1.606Keywords:
Post cholecystectomy Syndrome (PCS), Biliary Tract Disorders, Cholecystectomy ComplicationsAbstract
Post-cholecystectomy syndrome (PCS) is a medical condition that can develop after cholecystectomy. It is characterized by several gastrointestinal symptoms, including abdominal pain, dyspepsia, bloating, and diarrhea, which can limit patients' quality of life. Understanding the underlying cause, risk factors, and effective intervention is essential to improve patient safety in clinical practice. This study aims to evaluate the frequency of post-cholecystectomy syndrome (PCS), analyze its symptoms and demographic features, and identify likely risk factors. This observational longitudinal study included 200 patients who underwent laparoscopic cholecystectomy in the surgical department of Shaikh Zayed Hospital Lahore between Jan 1st, 2021, and Jan 1st, 2022. Data were retrieved from electronic medical records, and patients were followed for PCS. The data was analyzed using SPSS software, version 25. Of 200 patients, 45 (22.5%) were diagnosed with Pcs. The ratio of males to females was 1:1.64. Age ranges from 19-78, and most belong to the 5th decade of life. Common symptoms are right upper quadrant abdominal pain in 33 (73.3%), nausea in 23 (51.1%), dyspepsia, vomiting in 16 (35.6%), and presenting signs included right hypochondriac region tenderness in 18 (40%), jaundice and epigastric tenderness in 4 (8.9%) cases. Common causes included Psychiatric disease in 8 (17.8%), helicobacter pylori infection in 7 (15.6%), muscle pathology in 6 (13.3%), and gastritis in 5 (11.11%), respectively. Based on the results it can be concluded that to provide effective treatments for individuals with PCS, it is essential to take signs seriously, conduct a comprehensive evaluation to reach an accurate diagnosis and treat the underlying cause appropriately.
Downloads
References
Adrian, T., Savage, A., Bacarese-Hamilton, A., Wolfe, K., Besterman, H., and Bloom, S. (1986). Peptide YY abnormalities in gastrointestinal diseases. Gastroenterology 90, 379-384.
Aflah, M., and Muhar, A. M. (2022). Sindrom Pasca-Kolesistektomi. Cermin Dunia Kedokteran 49, 560-563.
Aldahshan, A. A. S., Salamah, A. R., Fayoumi, N. M., Alkhudaydi, S. A., Alhijji, M. K. M., Alnahwi, Q. A. A., Balghsoon, A. A., Alomran, A. O., Muhaisin, S., and Altalhi, B. I. H. (2021). An overview on post-cholecystectomy syndrome diagnostic & management approach. Archives of Pharmacy Practice¦ Volume 12, 39.
Alotaibi, A. M. (2023). Post-cholecystectomy syndrome: A cohort study from a single private tertiary center. Journal of Taibah University Medical Sciences 18, 383-389.
Freud, M., Djaldetti, M., De Vries, A., and Leffkowitz, M. (1960). Postcholecystectomy syndrome: a survey of 114 patients after biliary tract surgery. Digestion 93, 288-293.
Georgescu, D., Caraba, A., Ionita, I., Lascu, A., Hut, E. F., Dragan, S., Ancusa, O. E., Suceava, I., and Lighezan, D. (2022). Dyspepsia and gut microbiota in female patients with postcholecystectomy syndrome. International Journal of Women's Health, 41-56.
Girometti, R., Brondani, G., Cereser, L., Como, G., Del Pin, M., Bazzocchi, M., and Zuiani, C. (2010). Post-cholecystectomy syndrome: spectrum of biliary findings at magnetic resonance cholangiopancreatography. The British journal of radiology 83, 351-361.
Goyal, R. K., and Chaudhury, A. (2008). Physiology of normal esophageal motility. Journal of clinical gastroenterology 42, 610.
Isherwood, J., Oakland, K., and Khanna, A. (2019). A systematic review of the aetiology and management of post cholecystectomy syndrome. The Surgeon 17, 33-42.
Jaunoo, S., Mohandas, S., and Almond, L. (2010). Postcholecystectomy syndrome (PCS). International journal of surgery 8, 15-17.
Larmi, T., Mokka, R., Kemppainen, P., and Seppälä, A. (1975). A critical analysis of the cystic duct remnant. Surgery, Gynecology & Obstetrics 141, 48-52.
Lum, Y. W., House, M. G., Hayanga, A. J., and Schweitzer, M. (2006). Postcholecystectomy syndrome in the laparoscopic era. Journal of Laparoendoscopic & Advanced Surgical Techniques 16, 482-485.
Madacsy, L., Dubravcsik, Z., and Szepes, A. (2015). Postcholecystectomy syndrome: from pathophysiology to differential diagnosis-a critical review. Pancreat Disord Ther 5, 2.
Mertens, M. C., Roukema, J. A., Scholtes, V. P., and De Vries, J. (2010). Trait anxiety predicts unsuccessful surgery in gallstone disease. Psychosomatic medicine 72, 198-205.
Muller, E. L., Lewinski, M. A., and Pitt, H. A. (1984). The cholecysto-sphincter of Oddi reflex. Journal of Surgical Research 36, 377-383.
Saleem, S., Weissman, S., Gonzalez, H., Rojas, P. G., Inayat, F., Alshati, A., and Gaduputi, V. (2021). Post-cholecystectomy syndrome: a retrospective study analysing the associated demographics, aetiology, and healthcare utilization. Translational Gastroenterology and Hepatology 6.
Schofer, J. M. (2010). Biliary causes of postcholecystectomy syndrome. The Journal of emergency medicine 39, 406-410.
Shirah, B. H., Shirah, H. A., Zafar, S. H., and Albeladi, K. B. (2018). Clinical patterns of postcholecystectomy syndrome. Annals of Hepato-biliary-pancreatic Surgery 22, 52.
Skalicky, M. (2011). Dynamic changes of echogenicity and the size of the papilla of Vater before and after cholecystectomy. Journal of International Medical Research 39, 1051-1062.
Thieu, H., Dat, B. B., Nam, N. H., Reda, A., Duc, N. T., Alshareef, A., Nguyen, J. G., Ngoc, N. M., and Huy, N. T. (2020). Antibiotic resistance of Helicobacter pylori infection in a children's hospital in Vietnam: prevalence and associated factors. Minerva medica 111, 498-501.
Thurley, P. D., and Dhingsa, R. (2008). Laparoscopic cholecystectomy: postoperative imaging. American Journal of Roentgenology 191, 794-801.
Webb, T. H., Lillemoe, K. D., and Pitt, H. A. (1988). Gastrosphincter of Oddi reflex. The American journal of surgery 155, 193-198.
Womack, N. A., and Crider, R. L. (1947). The persistence of symptoms following cholecystectomy. Annals of surgery 126, 31.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 M RIZWAN, MI ANWAR , MH LAIQUE, T MEHMOOD, D JAVED, MA ASKARI, MZU ABID
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.