OUTCOMES OF PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION WITH CHRONIC TOTAL OCCLUSIONS

Authors

  • I UDDIN Department of Cardiology, Hayatabad Medical Complex, Peshawar, Pakistan
  • Dr SHIREEN Department of Cardiology, Liaquat University Hospital Pakistan
  • S GHAFFAR Department of Cardiology, Armed Forces Institute of Cardiology (AFIC), Pakistan
  • Z MALIK Department of Cardiology, University of Lahore, Pakistan
  • MO HASHMI Department of Cardiology, PIMS Islamabad, Pakistan
  • W JAMIL Department of Cardiology, Chaudry Pervaiz Elahi Institute of Cardiology, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.283

Keywords:

CTO, PCI, Risk Factors, TVR

Abstract

This study aimed to assess the efficacy of percutaneous coronary intervention (PCI) with chronic total occlusions (CTO) in a cardiology department in Peshawar, Pakistan, between January 2021 and December 2022. The study included 190 to 200 patients, most of whom had a history of hypertension and diabetes and were predominantly male. The successful CTO-PCI group had significantly lower major adverse cardiac events (MACE) and target vessel revascularization (TVR) rates than the failed CTO-PCI group. Younger age, male gender, absence of previous myocardial infarction, and lower J-CTO score were significant risk factors for CTO PCI success. Long-term outcomes indicated that CTO PCI was linked to lower rates of MACE, TVR, and repeat revascularization compared to non-CTO PCI. These results indicate that CTO-PCI can be a safe and efficient treatment option for patients with chronic total occlusions. Identification of significant risk factors can aid in selecting patients who are likely to benefit from this procedure. Further research is required to confirm these findings and examine the long-term outcomes of CTO-PCI in larger patient cohorts.

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References

Ali, W. E., and Bakris, G. L. (2018). Initial single-pill combinations for antihypertensive treatment: greater cardiovascular mortality reduction yet still not used. European Heart Journal 39, 3662-3663.

Bahadir Simsek, M., Spyridon Kostantinis, M., Karacsonyi, J., Khaldoon Alaswad, M., Michael Megaly, M., Karmpaliotis, D., Amirali Masoumi, M., Jaber, W. A., William Nicholson, M., and Rinfret, S. (2022). A systematic review and meta-analysis of clinical outcomes of patients undergoing chronic total occlusion percutaneous coronary intervention. Journal of Invasive Cardiology 34.

Brilakis, E. S., Mashayekhi, K., Tsuchikane, E., Abi Rafeh, N., Alaswad, K., Araya, M., Avran, A., Azzalini, L., Babunashvili, A. M., and Bayani, B. (2019). Guiding principles for chronic total occlusion percutaneous coronary intervention: a global expert consensus document. Circulation 140, 420-433.

Cruz-Gonzalez, I., Fuertes Barahona, M., Moreno-Samos, J. C., Barreiro-Perez, M., Rodríguez-Collado, J., Gonzalez-Calle, D., and Sanchez, P. L. (2017). Left atrial appendage occlusion in the presence of thrombus with a LAmbre device. JACC Cardiovasc Interv 10, 2224-6.

Danek, B. A., Karatasakis, A., Karmpaliotis, D., Alaswad, K., Yeh, R. W., Jaffer, F. A., Patel, M. P., Mahmud, E., Lombardi, W. L., and Wyman, M. R. (2016). Development and validation of a scoring system for predicting periprocedural complications during percutaneous coronary interventions of chronic total occlusions: the Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS CTO) complications score. Journal of the American Heart Association 5, e004272.

Galassi, A. R., Tomasello, S. D., Reifart, N., Werner, G. S., Sianos, G., Bonnier, H., Sievert, H., Ehladad, S., Bufe, A., and Shofer, J. (2011). In-hospital outcomes of percutaneous coronary intervention in patients with chronic total occlusion: insights from the ERCTO (European Registry of Chronic Total Occlusion) registry. EuroIntervention: journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 7, 472-479.

Galie, N., Hoeper, M. M., Humbert, M., Torbicki, A., Vachiery, J.-L., Barbera, J. A., Beghetti, M., Corris, P., Gaine, S., and Gibbs, J. S. (2009). Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). European heart journal 30, 2493-2537.

He, P., Yang, Y., and Hu, F. (2014). Transradial versus transfemoral percutaneous coronary intervention in elderly patients: a systematic overview and meta-analysis. Chinese Medical Journal 127, 1110-1117.

Megaly, M., Khalil, M., Basir, M. B., McEntegart, M. B., Spratt, J. C., Yamane, M., Tsuchikane, E., Xu, B., Alaswad, K., and Brilakis, E. S. (2021). Outcomes of successful vs. failed contemporary chronic total occlusion percutaneous coronary intervention. Cardiovascular Intervention and Therapeutics, 1-7.

Ong, P. J. L., and Wijns, W. C. (2016). Save your blushes and stop routine thrombus aspiration during primary PCI. Vol. 37, pp. 1899-1901. Oxford University Press.

Opolski, M. P., Gransar, H., Lu, Y., Achenbach, S., Al-Mallah, M. H., Andreini, D., Bax, J. J., Berman, D. S., Budoff, M. J., and Cademartiri, F. (2019). Prognostic value of chronic total occlusions detected on coronary computed tomographic angiography. Heart 105, 196-203.

Sapontis, J., Salisbury, A. C., Yeh, R. W., Cohen, D. J., Hirai, T., Lombardi, W., McCabe, J. M., Karmpaliotis, D., Moses, J., and Nicholson, W. J. (2017). Early procedural and health status outcomes after chronic total occlusion angioplasty: a report from the OPEN-CTO Registry (Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion Hybrid Procedures). JACC: Cardiovascular Interventions 10, 1523-1534.

Valenti, R., Vergara, R., Migliorini, A., Parodi, G., Carrabba, N., Cerisano, G., Dovellini, E. V., and Antoniucci, D. (2013). Predictors of reocclusion after successful drug-eluting stent–supported percutaneous coronary intervention of chronic total occlusion. Journal of the American College of Cardiology 61, 545-550.

Xenogiannis, I., Alaswad, K., Krestyaninov, O., Khelimskii, D., Khatri, J. J., Choi, J. W., Jaffer, F. A., Patel, M., Mahmud, E., and Doing, A. H. (2021). Impact of adherence to the hybrid algorithm for initial crossing strategy selection in chronic total occlusion percutaneous coronary intervention. Revista Española de Cardiología (English Edition) 74, 1023-1031.

Yudi, M. B., Love, B., Nadir, A., Kini, A., and Sharma, S. K. (2017). Percutaneous closure of left ventricular pseudoaneursym with septal occluder device and coils: a multimodality imaging approach. JACC: Cardiovascular Interventions 10, e159-e161.

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Published

2023-05-22

How to Cite

UDDIN , I., SHIREEN, D., GHAFFAR , S., MALIK, Z., HASHMI , M., & JAMIL, W. (2023). OUTCOMES OF PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION WITH CHRONIC TOTAL OCCLUSIONS. Biological and Clinical Sciences Research Journal, 2023(1), 283. https://doi.org/10.54112/bcsrj.v2023i1.283

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