FREQUENCY OF SUBCLINICAL HYPO AND HYPERTHYROIDISM IN PATIENTS PRESENTING WITH CONGESTIVE HEART FAILURE

Authors

  • H ANUM Department of cardiology, Rehmatul-lil-Alamen institute of cardiology, PESSI, Lahore, Pakistan
  • AE QURESHI Department of cardiology, Rehmatul-lil-Alamen institute of cardiology, PESSI, Lahore, Pakistan
  • N ULLAH Department of cardiology, Rehmatul-lil-Alamen institute of cardiology, PESSI, Lahore, Pakistan
  • M SAJJAD Department of Cardiology, Gulab Devi Hospital Lahore, Pakistan
  • U FAROOQ Department of cardiology, Rehmatul-lil-Alamen institute of cardiology, PESSI, Lahore, Pakistan
  • WA DAR Department of Cardiology, Punjab cardiac and medical center Ravi Road Lahore, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.235

Keywords:

Congestive heart failure, thyroid gland, thyroid stimulating hormone, body mass index, diabetes Mellitus

Abstract

Congestive heart failure is among the most common presentations in Cardiology inpatient and outpatient departments. It is associated with several long- and short-term complications and among these patients hypo and hyperthyroidism is found frequently. This study aims to determine the frequency of subclinical hypo or hyperthyroidism in cases with congestive heart failure. This cross-sectional study was conducted at the Rehmatul-Lol-Alameen institute of cardiology, PESSI, from 23-08-2020 to 22-02-2021. This study included cases of both genders aged 30-70 years suffering from congestive heart failure. Hypothyroidism was labeled when the TSH level was between 4.6 to 10 mIU/L, and hyperthyroidism was labeled when the TSH level was between 0.01 to 0.02 mIU/L. In this study, there were 91 cases of congestive HF. There were 61 (67.03%) males and 30 (32.97%) females. The mean age of the subjects was 2 51.53±9.23 years, and the mean weight was 75.71±15.18 kg. There were 20 (21.98%) cases with a history of DM. Hypothyroidism was observed in 19 (20.88%) of the cases, and hyperthyroidism in 08 (8.79%) of the cases. There was no significant difference in gender, age, BMI, duration of HF, and DM with hypo and hyperthyroidism. We can conclude from the study results that hypo and hyperthyroidism are common in cases with congestive heart failure, though hypothyroidism cases were found to be double than the hyperthyroidism.

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References

Akhtar, S., Khan, M., Siddiqui, N., and Nawab, G. (2001). Frequencies of thyroid problems in different age, se and seasons. Sciences 1, 153-6.

Altamish, M., Samuel, V. P., Dahiya, R., Singh, Y., Deb, P. K., Bakshi, H. A., Tambuwala, M. M., Chellappan, D. K., Collet, T., and Dua, K. (2020). Molecular signaling of G‐protein‐coupled receptor in chronic heart failure and associated complications. Drug development research 81, 23-31.

Åsvold, B. O., Bjøro, T., Nilsen, T. I. L., Gunnell, D., and Vatten, L. J. (2008). Thyrotropin levels and risk of fatal coronary heart disease: the HUNT study. Archives of internal medicine 168, 855-860.

Boekholdt, S. M., Titan, S. M., Wiersinga, W. M., Chatterjee, K., Basart, D. C., Luben, R., Wareham, N. J., and Khaw, K. T. (2010). Initial thyroid status and cardiovascular risk factors: the EPIC‐Norfolk prospective population study. Clinical endocrinology 72, 404-410.

Din, N., Latif, A., Rahman, A. U., Ali, S., and Parvez, M. (2022). Frequency of Hyperthyroidism among Patients with Congestive Heart Failure Presenting at Tertiary Care Hospital, Peshawar. Pakistan Journal of Medical & Health Sciences 16, 278-278.

Kim, H., Lee, H. N., and Ha, J. (2019). Association high-iodine-containing seaweed soup consumption after birth and subclinical hypothyroidism in Korean women: Korea National Health and Nutrition Examination Survey IV (2013–2015). International Journal of Thyroidology 12, 105-112.

Kim, Y. A., and Park, Y. J. (2014). Prevalence and risk factors of subclinical thyroid disease. Endocrinology and metabolism 29, 20-29.

Kuchulakanti, P. K., Bandaru, V., Kuchulakanti, A., Lakshumaiah, T., Rathod, M., Khare, R., Sairam, P., Reddy, P. R., Ravikanth, A., and Guruprakash, A. (2019). Association of subclinical hypothyroidism in heart failure: a study from South India. Br J Cardiol 26, 35.

Lisco, G., De Tullio, A., Iacoviello, M., and Triggiani, V. (2020). Congestive heart failure and thyroid dysfunction: the role of the low T3 syndrome and therapeutic aspects. Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets-Immune, Endocrine & Metabolic Disorders) 20, 646-653.

Naeem, A., Jan, S., and Shah, B. G. (2022). Association of the thyroid Function disorder with recurrent pregnancy loss in women: Thyroid Function Disorder with Recurrent Pregnancy Loss in Women. Pakistan BioMedical Journal, 274-277.

Piantanida, E., Ippolito, S., Gallo, D., Masiello, E., Premoli, P., Cusini, C., Rosetti, S., Sabatino, J., Segato, S., and Trimarchi, F. (2020). The interplay between thyroid and liver: implications for clinical practice. Journal of endocrinological investigation 43, 885-899.

Selmer, C., Olesen, J. B., Hansen, M. L., von Kappelgaard, L. M., Madsen, J. C., Hansen, P. R., Pedersen, O. D., Faber, J., Torp-Pedersen, C., and Gislason, G. H. (2014). Subclinical and overt thyroid dysfunction and risk of all-cause mortality and cardiovascular events: a large population study. The Journal of Clinical Endocrinology & Metabolism 99, 2372-2382.

Tittl, L., Marten, S., Naue, C., and Beyer-Westendorf, J. (2021). 5-year outcomes from rivaroxaban therapy in atrial fibrillation: Results from the Dresden NOAC Registry. Thrombosis Research 202, 24-30.

Vanderpump, M., Tunbridge, W., French, J., Appleton, D., Bates, D., Clark, F., Evans, J. G., Rodgers, H., Tunbridge, F., and Young, E. (1996). The development of ischemic heart disease in relation to autoimmune thyroid disease in a 20-year follow-up study of an English community. Thyroid 6, 155-160.

Ye, Y., Xie, H., Zeng, Y., Zhao, X., Tian, Z., and Zhang, S. (2014). Association between subclinical hypothyroidism and blood pressure-a meta-analysis of observational studies. Endocrine Practice 20, 150-158.

Yezli, S., Mushi, A., Almuzaini, Y., Balkhi, B., Yassin, Y., and Khan, A. (2021). Prevalence of diabetes and hypertension among Hajj pilgrims: a systematic review. International journal of environmental research and public health 18, 1155.

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Published

2023-04-10

How to Cite

ANUM, H., QURESHI, A., ULLAH, N., SAJJAD, M., FAROOQ, U., & DAR, W. (2023). FREQUENCY OF SUBCLINICAL HYPO AND HYPERTHYROIDISM IN PATIENTS PRESENTING WITH CONGESTIVE HEART FAILURE. Biological and Clinical Sciences Research Journal, 2023(1), 235. https://doi.org/10.54112/bcsrj.v2023i1.235

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