Comparison of 3 Port vs 4 Port Laparoscopic Cholecystectomy for Gallstone Disease

Authors

  • Mahrukh Shafiq Department of General Surgery, FRPMC PAF Hospital Karachi, Pakistan
  • Rohit Kumar Department of General Surgery, PNS Shifa Hospital Karachi, Pakistan
  • Aun Ali Department of General Surgery, FRPMC PAF Hospital Karachi, Pakistan
  • Muhammad Khurram Zia Department of General Surgery, Liaquat College of Medicine and Dentistry and Darul Sehat Hospital Karachi, Pakistan
  • Mansoor Iqbal Department of General Surgery, FRPMC PAF Hospital Karachi, Pakistan
  • Yousuf Lakdawala Department of General Surgery, FRPMC PAF Hospital Karachi, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v6i6.1901

Keywords:

Cholecystectomy, Laparoscopic; Gallstones; Pain Measurement; Postoperative Complications

Abstract

Laparoscopic cholecystectomy (LC) is the gold standard for treating symptomatic gallstones. Conventionally performed with four ports, the three-port modification has been proposed to reduce surgical trauma, postoperative pain, and recovery time. However, evidence comparing the safety and outcomes of three-port versus four-port LC in the Pakistani population remains limited. Objective: To evaluate and compare the clinical outcomes and perioperative risks of three-port LC with four-port LC. Methods: This randomised comparative study was conducted at F.R.P.M.C. PAF Hospital, Karachi, from 1 August 2023 to 1 July 2024, following ethical approval. A total of 60 patients aged 18–60 years of both genders, classified as ASA I or II, and scheduled for elective LC were recruited through non-probability consecutive sampling. Patients were randomised into two groups: three-port LC and four-port LC. Intraoperative complications, conversion to open surgery, length of hospital stay, postoperative pain (assessed by a standardised pain score), and recovery time were compared. Statistical analysis was performed using appropriate parametric and non-parametric tests, with p<0.05 considered significant. Results: Intraoperative complications were lower in the three-port group compared with the four-port group (17% vs. 40%, p=0.09). Conversion to open surgery occurred in 27% of three-port and 40% of four-port cases (p=0.255). The mean hospital stay was significantly shorter in the three-port group (2.8±0.6 days) than in the four-port group (3.5±0.7 days) (p<0.0001). Postoperative pain scores were also significantly lower in the three-port group (5.7±0.9) compared to the four-port group (6.5±0.9) (p=0.001). Furthermore, recovery time was faster in the three-port group (14.9±1.4 days) compared with the four-port group (17.2±1.5 days) (p<0.0001). Conclusion: Three-port LC is a safe and effective alternative to conventional four-port LC, offering shorter hospitalisation, reduced postoperative pain, faster recovery, and enhanced patient satisfaction, without increasing intraoperative risks.

Downloads

Download data is not yet available.

References

Sun H, Warren J, Yip J, Ji Y, Hao S, Han W, et al. Factors influencing gallstone formation: a review of the literature. Biomolecules. 2022;12(4):550. https://doi.org/10.3390/biom12040550

Mannam R, Sankara Narayanan R, Bansal A, Yanamaladoddi VR, Sarvepalli SS, Vemula SL, et al. Laparoscopic cholecystectomy versus open cholecystectomy in acute cholecystitis: a literature review. Cureus. 2023;15(9):e45704. https://doi.org/10.7759/cureus.45704

Alkatout I, Mechler U, Mettler L, Pape J, Maass N, Biebl M, et al. The development of laparoscopy—a historical overview. Front Surg. 2021;8:799442. https://doi.org/10.3389/fsurg.2021.799442

Jelinek LA, Marietta M, Jones MW. Surgical access incisions. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan– [cited 2025 Aug 21]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541018/

Pasquer A, Ducarroz S, Lifante JC, Skinner S, Poncet G, Duclos A. Operating room organization and surgical performance: a systematic review. Patient Saf Surg. 2024;18(1):5. https://doi.org/10.1186/s13037-023-00388-3

Kim HC, Song Y, Lee JS, Jeong ME, Lee Y, Lim JH, et al. Comparison of pharmacologic therapies alone versus operative techniques in combination with pharmacologic therapies for postoperative analgesia in patients undergoing laparoscopic cholecystectomy: a randomized controlled trial. Int J Surg. 2022;104:106763. https://doi.org/10.1016/j.ijsu.2022.106763

Kumar A, Prakash S, Verma R. Comparison of three-port versus four-port laparoscopic cholecystectomy. Asian J Med Sci. 2024;15(1):235–9. https://doi.org/10.3126/ajms.v15i1.55752

Mohamed AAE-A, Zaazou MMT. Three-port versus conventional four-port laparoscopic cholecystectomy: a comparative study. Egypt J Surg. 2020;39(1):119–23. https://doi.org/10.4103/ejs.ejs_149_19

Fisher AT, Bessoff KE, Khan RI, Touponse GC, Yu MMK, Patil AA, et al. Evidence-based surgery for laparoscopic cholecystectomy. Surg Open Sci. 2022;10:116–34. https://doi.org/10.1016/j.sopen.2022.08.003

Rocha FG, Clanton J. Technique of cholecystectomy: open and minimally invasive. In: Jarnagin WR, editor. Blumgart’s surgery of the liver, biliary tract and pancreas. 6th ed. Philadelphia: Elsevier; 2017. p. 569–84.e2. https://doi.org/10.1016/B978-0-323-34062-5.00035-2

Chauhan H, Kothiya J, Savsaviya J. Three port versus four port laparoscopic cholecystectomy: a prospective comparative clinical study. Int Surg J. 2020;7(11):3666–9. https://doi.org/10.18203/2349-2902.isj20204669

Nip L, Tong KS, Borg CM. Three-port versus four-port technique for laparoscopic cholecystectomy: systematic review and meta-analysis. BJS Open. 2022;6(2):zrac013. https://doi.org/10.1093/bjsopen/zrac013

González-Muniesa P, Mártinez-González M-A, Hu FB, Després J-P, Matsuzawa Y, Loos RJF, et al. Obesity. Nat Rev Dis Primers. 2017;3(1):17034. https://doi.org/10.1038/nrdp.2017.34

Shah MY, Somasundaram U, Wilkinson T, Wasnik N. Feasibility and safety of three-port laparoscopic cholecystectomy compared to four-port laparoscopic cholecystectomy. Cureus. 2021;13(11):e19979. https://doi.org/10.7759/cureus.19979

Akay T, Örün S, Leblebici M. Three-port versus standard four-port laparoscopic cholecystectomy: a clinical trial. Laparosc Endosc Surg Sci. 2019;26(4):175–80. https://doi.org/10.14744/less.2020.93764

Beltzer C, Burghard A, Kühnert N, Schmidt R. Feasibility and safety of laparoscopic 3-port cholecystectomy using the LiVac retractor: a prospective cohort study. Ann Laparosc Endosc Surg. 2023;8:22. https://doi.org/10.21037/ales-22-48

Lin G, Wang X, Ma J, Sun W, Han C, Tang L. Fast-track surgery with three-port versus conventional perioperative management of bladder cancer associated laparoscopic radical cystectomy and ileal conduit diversion: Chinese experience. World J Surg Oncol. 2024;22(1):204. https://doi.org/10.1186/s12957-024-03480-9

Wang D, Luo Z, Ming J. Clinical benefits of the 5th intercostal incision in uniportal VATS for female patients. Sci Rep. 2025;15(1):4158. https://doi.org/10.1038/s41598-025-88797-5

Tariq M, Hafeez M, Fatima F, Khalid U, Ateeque S, Zainab A, et al. Three-port versus four-port laparoscopic cholecystectomy: a two years experience at two armed forces tertiary care hospitals. Pak Armed Forces Med J. 2020;70(2):402–8.

Downloads

Published

2025-06-30

How to Cite

Shafiq, M. ., Kumar, R. ., Ali, A. ., Zia, M. K. ., Iqbal, M. ., & Lakdawala, Y. . (2025). Comparison of 3 Port vs 4 Port Laparoscopic Cholecystectomy for Gallstone Disease. Biological and Clinical Sciences Research Journal, 6(6), 261–264. https://doi.org/10.54112/bcsrj.v6i6.1901

Issue

Section

Original Research Articles

Most read articles by the same author(s)