RISK FACTORS OF CHRONIC KIDNEY DISEASE

MS LODHI; B FAROOQ; ZH QURESHI; FA MALIK; MJ KHAN

doi:10.54112/bcsrj.v2023i1.368

Authors

MS LODHI Institute of Molecular Biology and Biotechnology, The University of Lahore, Pakistan
B FAROOQ Department of Biochemistry, Nishtar Medical University & Hospital Multan, Pakistan
ZH QURESHI Department of Physiology, Multan Medical, and Dental College (MMDC) Multan, Pakistan
FA MALIK Department of Biochemistry, DG Khan Medical College DG Khan, Pakistan
MJ KHAN Molecular Pathology Laboratory, Nishtar Medical University & Hospital Multan, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.368

Keywords:

Chronic kidney disease, End stage renal disease, Risk factors

Abstract

The prospective study was conducted in Tertiary Care Hospitals from June 2022 to June 2023 to evaluate risk factors for CKD in the local population. Six hundred subjects were included in the study who were screened for the risk factors of chronic kidney disease. The participants were screened for CKD using a questionnaire. CKD-EPI equation was used for exploring disease burden. Results showed that CKD subjects were more likely male, older, urban residents, were obese or overweight, and had cardiovascular disease, hypertension, and diabetes compared to those without CKD. In subjects with CKD, the most common risk factors were diabetes(32%), hypertension (65%), and anemia (40%). Sensitivity analysis was done using CKD – EPI equation, and results were compared with the MDRD-3 equation. The prevalence of CKD, according to CKD-EPI, was 16%. Prevalence of CKD stages I, II, III, IV, and V was 9%, 4.5%,4.5%,1%, and 1%, respectively. People were not well aware of the status of their condition. Primary care centers should screen patients with diabetes and hypertension for kidney disease. Early detection can retard progression and improve outcomes.

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