COMPARISON OF PROPHYLACTIC DOSE OF TRAMADOL AND DEXAMETHASONE IN PREVENTING SHIVERING IN PATIENTS UNDERGOING SUBARACHNOID BLOCK

Authors

  • MR BUTT Department of anesthesiology, Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan
  • HM JAVED Department of anesthesiology, Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan
  • MA ASHFAQ Department of anesthesiology, Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan
  • A IQBAL Department of anesthesiology, Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan
  • MM ZAHID Department of surgery, Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan
  • M KHALID Department of anesthesiology, Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2023i1.331

Keywords:

Dexamethasone, Tramadol, Prophylaxis

Abstract

This study aimed to assess the prophylactic efficacy of Tramadol and Dexamethasone in preventing shivering following spinal anesthesia. A total of 162 patients aged 18 to 60, with ASA physical status I or II, undergoing various surgical procedures, were randomly assigned to receive intravenous normal saline (Group C), intravenous tramadol at a dose of 1 mg/kg (Group T), or intravenous dexamethasone at a dose of 0.1 mg/kg (Group D). The occurrence of shivering, its impact, and the onset of dizziness, nausea, and perspiration were documented. Baseline demographics, body temperature, type of operation, sensory blockade level, duration of surgery, and anesthesia were comparable among patients. Shivering was observed in 42 out of 162 patients (25.92%). Shivering occurred in 24 patients in the placebo group, 11 in Group D, and 7 in Group T. A statistically significant difference was found between Group T and Group C (p = 0.004). However, there was no significant difference between Group T and Group D (p = 0.771). Hallucination was reported in 1 patient (1.85%) in Group T. In conclusion, tramadol at a dose of 1 mg/kg effectively reduces shivering induced by spinal anesthesia compared to a placebo. Nevertheless, our study did not find a statistically significant difference between intravenous tramadol at 1 mg/kg and intravenous Dexamethasone at 0.1 mg/kg.

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References

Asaad, O. M., Hafez, M., Mohamed, M. Y., and El-Mahgoup, S. S. (2011). Comparative study between prophylactic single dose of fentanyl and dexmedetomidine in the management of agitation after sevoflurane anesthesia in children. Egyptian Journal of Anaesthesia 27, 31-37.

Avais, B., Javed, H., Sheikh, N., Sheikh, M., Jamshaid, B., and Butt, Z. (2022). COMPARISON OF KETAMINE AND TRAMADOL FOR PREVENTION OF SHIVERING DURING SPINAL ANESTHESIA. Biological and Clinical Sciences Research Journal 2022.

Baldo, B. A., and Rose, M. A. (2020). The anaesthetist, opioid analgesic drugs, and serotonin toxicity: a mechanistic and clinical review. British journal of anaesthesia 124, 44-62.

Beck, C. E., Sümpelmann, R., Nickel, K., Keil, O., Kuebler, J. F., Boethig, D., Witt, L., and Dennhardt, N. (2020). Systemic and regional cerebral perfusion in small infants undergoing minor lower abdominal surgery under awake caudal anaesthesia: an observational study. European Journal of Anaesthesiology| EJA 37, 696-700.

Bindu, B., Bindra, A., and Rath, G. (2017). Temperature management under general anesthesia: Compulsion or option. Journal of anaesthesiology, clinical pharmacology 33, 306.

Blondin, D. P., and Haman, F. (2018). Shivering and nonshivering thermogenesis in skeletal muscles. Handbook of clinical neurology 156, 153-173.

Flecknell, P., Lofgren, J. L., Dyson, M. C., Marini, R. R., Swindle, M. M., and Wilson, R. P. (2015). Preanesthesia, anesthesia, analgesia, and euthanasia. In "Laboratory animal medicine", pp. 1135-1200. Elsevier.

Heravi, A. (2022). THE MANAGEMENT OF PAIN SYNDROME AND THE PRINCIPLES OF ANESTHETIC MANAGEMENT IN PERIOPERATIVE PERIOD, Ternopil.

Igweagu, I. K. (2014). SHIVERING DURING CAESAREAN DELIVERY UNDER SPINAL ANAESTHESIA: THE ROLE OF PETHIDINE ADDED TO INTRATHECAL BUPIVACAINE. Faculty of Anaesthesia.

Khan, M. J., Babar, A., Haq, I. U., Wadud, R., Farid, K., and Waheed, A. (2022). Comparison of Ultrasound-Guided Ankle Block Versus Anatomical Landmark-Guided Ankle Block in Ankle and Foot Surgery Under Regional Anesthesia. Pakistan Journal of Medical & Health Sciences 16, 652-652.

Layton, R., Layton, D., Beggs, D., Fisher, A., Mansell, P., and Stanger, K. J. The impact of stress and anesthesia on animal models of infectious.

Layton, R., Layton, D., Beggs, D., Fisher, A., Mansell, P., and Stanger, K. J. (2023). The impact of stress and anesthesia on animal models of infectious disease. Frontiers in Veterinary Science 10, 1086003.

McSwain, J. R., Yared, M., Doty, J. W., and Wilson, S. H. (2015). Perioperative hypothermia: Causes, consequences and treatment. World Journal of Anesthesiology 4, 58-65.

Renaningtyastutik, Y., Lumadi, S. A., and Handian, F. I. (2022). The relationship between operation duration and shivering in post-spinal anaesthesia patients. The Journal of Palembang Nursing Studies 1, 107-114.

Vinathi, G. A., and Latha, V. S. (2018). Efficacy and potency of dexamethasone in comparison with ketamine and tramadol in the prevention of post-operative shivering. IOSR J Dent Med Sci 17, 66-72.

Yun, Y., Wang, J., Tang, R. R., Yin, X. R., Zhou, H., and Pei, L. (2017). Effects of an intraoperative dexmedetomidine bolus on the postoperative blood pressure and pain subsequent to craniotomy for supratentorial tumors. Journal of Neurosurgical Anesthesiology 29, 211-218.

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Published

2023-06-27

How to Cite

BUTT , M., JAVED , H., ASHFAQ , M., IQBAL , A., ZAHID , M., & KHALID , M. (2023). COMPARISON OF PROPHYLACTIC DOSE OF TRAMADOL AND DEXAMETHASONE IN PREVENTING SHIVERING IN PATIENTS UNDERGOING SUBARACHNOID BLOCK. Biological and Clinical Sciences Research Journal, 2023(1), 331. https://doi.org/10.54112/bcsrj.v2023i1.331

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