Intraoperative Partial Pressure of Oxygen Measurement to Predict Flap Survival

Authors

  • Muhammad Raza Tahir Department of Plastic Surgery Jinnah Burn and Reconstructive Surgery Center, Lahore, Pakistan
  • Kamran Khalid Department of Plastic Surgery Jinnah Burn and Reconstructive Surgery Center, Lahore, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v6i2.1573

Keywords:

Flap Survival, Intraoperative Po₂, Diff-Po₂, Reconstructive Surgery, Necrosis Risk, Pedicled Flaps

Abstract

Flap survival is a critical factor in reconstructive surgery, with ischemia-related complications leading to necrosis and surgical failure.
Current methods for intraoperative flap assessment are often subjective, creating a need for an objective, real-time measure of tissue viability. The
partial pressure of oxygen (pO₂) may serve as a reliable predictor of flap survival, allowing for early intervention and improved surgical outcomes.
Objective: Our study set out to explore whether the intraoperative measurement of the partial pressure of oxygen (pO₂) could reliably predict flap
survival in reconstructive surgery, aiming to pinpoint a practical tool for surgeons to assess tissue viability during operations. Methods: We enrolled
70 patients, all aged 18 years and above, who were undergoing flap procedures at our institution. Flap types varied across pedicled, free,
fasciocutaneous, and musculocutaneous designs. Intraoperatively, we maintained a consistent fraction of inspired oxygen at 50% and, at 30 minutes
post-flap inset, collected capillary blood samples from proximal, middle, and distal flap regions, alongside a fingertip control, using heparinised
syringes. These samples were analysed with a blood gas machine to determine pO₂ and diff-pO₂ values, while flap survival was later judged clinically
by tissue health, with complications like thrombosis or hematoma noted during surgery. Results: The mean flap pO₂ stood at 105.34 mmHg (±21.479),
finger pO₂ at 149.20±16.909 mmHg, and diff-pO₂ at 75.81±26.417 mmHg. Survival reached 82.9%, while complications were sparse, showing
thrombosis in 7.1% and hematoma in 4.3%. Pedicled flaps, making up 57.1% of cases, appeared most prone to necrosis. Conclusion: We conclude
that this approach could guide timely interventions, though further refinement of pO₂ cutoffs and risk factors is needed to sharpen its clinical impact.

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References

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Published

2025-02-28

How to Cite

Tahir, M. R. ., & Khalid, K. . (2025). Intraoperative Partial Pressure of Oxygen Measurement to Predict Flap Survival. Biological and Clinical Sciences Research Journal, 6(2), 87–89. https://doi.org/10.54112/bcsrj.v6i2.1573

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Original Research Articles