FETAL OUTCOME OF PREGNANCY WITH PRETERM PREMATURE RAPTURE OF MEMBRANE AT SHAIKH ZAID WOMEN HOSPITAL, LARKANA SINDH

Abstract

Preterm premature rupture of membranes (PPROM) is a multifactorial condition that can significantly influence fetal outcomes, primarily through complications linked to preterm birth and increased vulnerability to infections Objective: The main objective of the study is to find the fetal outcome of pregnancy with the preterm premature rupture of membrane at Shaikh Zaid Women Hospital, Larkana Sindh Methods: This research utilises descriptive cross-sectional fetal outcomes In pregnancies complicated by preterm premature rupture of membranes (PPROM). The study is conducted in the Department of Obstetrics and Gynecology at Shaikh Zaid Women’s Hospital in Larkana, Sindh from 1st September 2023 to 28 February 2024. The sample size calculation is based on previous studies, particularly considering early fetal death as a sensitive outcome, with an incidence rate of 14.3%. Results: Data were collected from 74 patients and the mean age of participants was 30.98 years (± 5.12), with an average BMI of 27.5 kg/m² (± 4.3), reflecting a moderately high weight profile among the cohort. Most participants (60%) were multigravidas, while 40% were experiencing their first pregnancy (primigravidas). Additionally, 65% of the participants belonged to a lower socioeconomic status, which may have influenced their access to prenatal care and associated pregnancy outcomes. A prior history of PPROM was noted in 20% of cases, while 25% of participants had a urinary tract infection, and 18% had a vaginal infection, both of which are known risk factors. Smoking was reported by 10% of the mothers, and a majority (65%) belonged to a lower socioeconomic status. Conclusion: It is concluded that preterm premature rupture of membranes (PPROM) significantly impacts neonatal outcomes, increasing the risks of complications such as low birth weight, respiratory distress, and infections.