IN-HOSPITAL OUTCOMES AMONG PATIENTS PRESENTED WITH ST-ELEVATION MYOCARDIAL INFARCTION TREATED WITH PRIMARY PERCUTANEOUS CORONARY INTERVENTION

MT JAN; MA KHAN; M NOMAN; H ULLAH; K ALAM; M RIAZ

doi:10.54112/bcsrj.v2024i1.1229

Authors

MT JAN Department of Cardiology, Hayatabad Medical Complex Peshawar, Pakistan
MA KHAN Department of Cardiology, Hayatabad Medical Complex Peshawar, Pakistan
M NOMAN Department of Cardiology, Lady Reading Hospital Peshawar, Pakistan
H ULLAH Department of Cardiology, Government Timergara Teaching Hospital, Dir Lower, Pakistan
K ALAM Department of Medicine, St. Francis Medical Center, Richmond, Virginia, USA
M RIAZ Department of Radiology, Peshawar Institute of Cardiology, Peshawar, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v2024i1.1229

Keywords:

ST-Elevation Myocardial Infarction, Primary Percutaneous Coronary Intervention, In-Hospital Outcomes, TIMI Flow, Door-to-Balloon Time, Mortality

Abstract

Primary Percutaneous Coronary Intervention (PCI) is considered the gold standard treatment for patients with ST-elevation myocardial Infarction (STEMI). Prompt intervention, aimed at restoring blood flow, plays a critical role in improving survival and minimizing complications in these patients. Objective: The objective of this study was to evaluate in-hospital outcomes among patients diagnosed with STEMI and treated with Primary PCI. Methods: This cross-sectional study was conducted in the Cardiology Department over one year. The study included patients aged 50 years and older who were diagnosed with STEMI based on electrocardiographic criteria and presented within 12 hours of symptom onset. Demographic information, clinical characteristics, comorbidities, and in-hospital outcomes were recorded. Statistical analyses were performed using relevant descriptive measures. Results: A total of 150 patients were included in the study. The mean age of patients was 60.89 ± 5.65 years, with 64.4% being male. The average door-to-balloon time was 89.93 ± 18.12 minutes. Successful reperfusion, defined as achieving a TIMI grade 3 flow, was observed in 87.8% of the patients. In-hospital mortality was recorded at 4.4%, while 3.3% of patients developed infections during their hospital stay. Conclusion: The study demonstrated favourable in-hospital outcomes for STEMI patients treated with Primary PCI, with a high success rate in achieving TIMI grade 3 flow and a relatively low in-hospital mortality rate. These findings underscore the efficacy of timely PCI in improving survival and procedural outcomes in STEMI patients, particularly when door-to-balloon time is minimized.

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References

Hoole SP, Bambrough P. Recent advances in percutaneous coronary intervention. Heart. 2020;106(18):1380-6.

Al-Lamee RK, Nowbar AN, Francis DP. Percutaneous coronary intervention for stable coronary artery disease. Heart. 2019;105(1):11-9.

Pascual I, Avanzas P, Almendárez M, Lorca R, Vigil-Escalera M, Arboine L, et al. STEMI, primary percutaneous coronary intervention and recovering of life expectancy: insights from the SurviSTEMI study. Revista Española de Cardiología (English Edition). 2021;74(10):829-37.

Batchelor R, Liu DH, Bloom J, Noaman S, Chan W. Association of periprocedural intravenous morphine use on clinical outcomes in ST‐elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention: Systematic review and meta‐analysis. Catheterization and Cardiovascular Interventions. 2020;96(1):76-88.

Wilson PW. Established risk factors and coronary artery disease: the Framingham Study. Am J Hypertens. 1994;7(7 Pt 2):7-12.

Canto JG, Kiefe CI, Rogers WJ, Peterson ED, Frederick PD, French WJ. NRMI Investigators. Number of coronary heart disease risk factors and mortality in patients with first myocardial infarction. JAMA. 2011;306(19):2120-7.

Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al, American Heart Association Statistics Committee. Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation. 2016;133(4):e38-360.

Iqbal R, Jahan N, Hanif A. Epidemiology and management cost of myocardial infarction in North Punjab, Pakistan. Iranian Red Crescent Medical Journal. 2015;17(7):28-35

Hafeez S, Javed A, Kayani AM. Clinical profile of patients presenting with acute ST elevation myocardial infarction. JPMA. The Journal of the Pakistan Medical Association. 2010;60(3):190-5.

Akhtar A, Saleemi MS, Zarlish QM, Arshad MB, Hashmi KA, Ghafoor H. Experience and Outcomes of Primary Percutaneous Coronary Intervention in a Tertiary Care Hospital in South Punjab, Pakistan. Cureus. 2023;15(12):e50024.

Barbosa RR, da Silva VR, Serpa RG, Cesar FB, Mauro VF, dos Reis Bayerl DM, Veloso WU, de Almeida Cesar R, Reseck PA. Gender differences in primary percutaneous coronary intervention outcomes in patients with ST-elevation myocardial infarction. Revista Brasileira de Cardiologia Invasiva (English Edition). 2015;23(2):96-101.

Cornara S, Somaschini A, De Servi S, Crimi G, Ferlini M, Baldo A, et al. Prognostic Impact of in-Hospital-Bleeding in Patients With ST-Elevation Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention. Am J Cardiol. 2017;120(10):1734-1741.

Piccaro de Oliveira P, Gonzales V, Lopes RD, Schmidt MM, Garofallo S, Santos RP, et al. Serious infections among unselected patients with ST-elevation myocardial infarction treated with contemporary primary percutaneous coronary intervention. Am Heart J. 2016;181:52-59.

Garberich RF, Traverse JH, Claussen MT, Rodriguez G, Poulose AK, Chavez IJ, Rutten-Ramos S, Hildebrandt DA, Henry TD. ST-elevation myocardial infarction diagnosed after hospital admission. Circulation. 2014;129(11):1225-32.