Evaluation of Causative Organisms in Surgical Site Infections
DOI:
https://doi.org/10.54112/bcsrj.v6i6.2365Keywords:
Surgical site infection, elective abdominal surgery, Escherichia coli, Staphylococcus aureus, causative organisms.Abstract
Surgical site infections are common postoperative complications that increase morbidity, hospital stay, and healthcare costs. Identification of causative organisms is essential for guiding appropriate antimicrobial therapy and infection-control practices. Objective: To determine the frequency of causative organisms in patients with surgical site infections after elective abdominal surgery. Methods: One hundred eighteen patients aged 18 to 70 years, of either gender, who developed surgical site infection within 30 days of elective abdominal surgery were included from 06-February-2025 to 06-May-2025 in the Department of Surgery, Mardan Medical Complex, Mardan. Diagnosis was based on visual inspection showing purulent drainage from the surgical site accompanied by redness, swelling, and warmth. Causative organisms such as Escherichia coli, Staphylococcus aureus, Klebsiella species, Proteus species, and Pseudomonas species were assessed. Data were analyzed using SPSS 25. Results: The mean age of 118 patients was 45.50±14.92 years, and the mean BMI was 25.14±2.05 kg/m². Males were 63 (53.4%). Escherichia coli was the most frequently isolated causative organism in 43 (36.4%) cases, followed by Staphylococcus aureus in 29 (24.6%) cases, Klebsiella in 25 (21.2%) cases, Proteus in 11 (9.3%) cases, and Pseudomonas in 10 (8.5%) cases. Conclusion: The most frequent causative organisms in patients with surgical site infections after elective abdominal surgery were Escherichia coli (36.4%), followed by Staphylococcus aureus (24.6%) and Klebsiella (21.2%).
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References
1. Seidelman JL, Mantyh CR, Anderson DJ. Surgical site infection prevention: a review. *JAMA.* 2023;329(3):244–52.
2. Curcio D, Cane A, Fernández F, Correa J. Surgical site infection in elective clean and clean-contaminated surgeries in developing countries. *Int J Infect Dis.* 2019;80:34–45.
3. Warren DK, Nickel KB, Wallace AE, Mines D, Tian F, Symons WJ, et al. Risk factors for surgical site infection after cholecystectomy. *Open Forum Infect Dis.* 2017;4(2).
4. Elbur AI, Yousif MA, El-Sayed ASA, Abdel-Rahman ME. Prophylactic antibiotics and wound infection. *J Clin Diagn Res.* 2013;7(12):2747–51.
5. Sayed-Hassan A, Hermann R, Chidiac F, Truy E, Guevara N, Bailleux S, et al. Association of the duration of antibiotic therapy with major surgical site infection in cochlear implantation. *JAMA Otolaryngol Head Neck Surg.* 2019;145(1):14–20.
6. Monahan M, Jowett S, Pinkney T, Brocklehurst P, Morton DG, Abdali Z, et al. Surgical site infection and costs in low- and middle-income countries: a systematic review of the economic burden. *PLoS One.* 2020;15(6).
7. van der Slikke EC, An AY, Hancock REW, Bouma HR. Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities. *EBioMedicine.* 2020;61:103044.
8. Troughton R, Birgand G, Johnson AP, Naylor N, Gharbi M, Aylin P, et al. Mapping national surveillance of surgical site infections in England: needs and priorities. *J Hosp Infect.* 2018;100(4):378–85.
9. Bashir J, Sahito RA, Abbasi MA, Jabeen A. Surgical site infection: evaluation of causative organisms involved. *Professional Med J.* 2015;22(2):181–5.
10. Alkaaki A, Al-Radi OO, Khoja A, Alnawawi A, Alnawawi A, Maghrabi A, et al. Surgical site infection following abdominal surgery: a prospective cohort study. *Can J Surg.* 2019;62(2):111–7.
11. Mustafa F, Khan MA, Mustafa A, Manzoor A, Safa S, Khogyani S. Common organisms causing surgical site infection in postoperative patients in a tertiary care hospital. *J Rawalpindi Med Coll.* 2022;26(4):633–6.
12. Qadir M, Bukhari N, Afridi F. Surveillance of surgical site wound infections after gynaecological and obstetrical surgeries in a tertiary care hospital. *Khyber J Med Sci.* 2023;16(2):78–82.
13. Malik AZ, Ali Q. Surgical site infections after elective surgery in Pakistan: SURGIPAK study. *J Rawalpindi Med Coll.* 2015;19(3):209–14.
14. Ghous F, Sarwar M, Faisal MS. Frequency of surgical site infection after emergency abdominal surgeries: an audit of 200 cases at a tertiary care unit. *Proc Shaikh Zayed Postgrad Med Inst.* 2018;32(1):29–34.
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Copyright (c) 2025 Palwasha Javed, Muhammad Hussain, Ghazala Rahim, . Anita, Maryam Sadiq, Laraib Zulfiqar

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