Comparison of Maternal and Perinatal Complications in Preterm and Term Preeclampsia

Authors

  • Faryal Khan Department of Obstetrics & Gynaecology, Lady Reading Hospital, Peshawar, Pakistan
  • Farnaz Zahoor Department of Obstetrics & Gynaecology, Lady Reading Hospital, Peshawar, Pakistan
  • Sidra Hassan Khel Department of Obstetrics & Gynaecology, Lady Reading Hospital, Peshawar, Pakistan
  • Humaira Gul Department of Obstetrics & Gynaecology, Hayatabad Medical Complex, Peshawar, Pakistan

DOI:

https://doi.org/10.54112/bcsrj.v6i5.2221

Keywords:

Preterm birth, perinatal outcome, neonatal morbidity, gestational diabetes, respiratory distress syndrome

Abstract

Preterm birth remains a major contributor to adverse maternal and neonatal outcomes, particularly in low- and middle-income settings. Comparative local data on maternal and perinatal complications in preterm versus term pregnancies may help guide risk stratification and perinatal care. Objective: To compare maternal and perinatal complications in preterm and term preeclampsia. Methodology: The present study was conducted on 120 pregnant women with preeclampsia aged 18 to 40 years from September 14, 2024, to March 14, 2025. Women with multiple pregnancies, major fetal anomalies, or incomplete records were not included. Patients were divided equally into two groups; group A had women with preterm pregnancies with preeclampsia, while group B had women with term pregnancies with preeclampsia. Maternal and perinatal complications were assessed in these women, which included maternal complications like c-section, gestational diabetes, and anaemia, while perinatal complications included low birth weight, neonatal intensive care unit (NICU) admission, respiratory distress syndrome (RDS), and neonatal jaundice. SPSS 27 was used for data analysis. Results: In the present study, the mean maternal age was 26.30±5.469 years in the preterm group and 27.67±6.422 years in the term group. Gestational diabetes was more frequent in the preterm group 13.3% while 3.3% in the term group (p = 0.04). Caesarean section was performed in 28.3% patients in the preterm group, and 11.7% in term deliveries (p = 0.02). Admission to the NICU was required for 33.3% infants in the preterm group, and 16.7% in the term group (p = 0.03). Respiratory distress syndrome occurred in 18.3% infants in the preterm group and 5.0% in term neonates (p = 0.02). Low birth weight was more frequent in preterm infants 26.7% compared to 11.7% in the term group (p = 0.03). Neonatal jaundice was diagnosed in 16.7% neonates in the preterm group and 3.3% (n=2) in term newborns (p = 0.01). Conclusion: Women with preterm pregnancy were at a higher risk of maternal complications such as gestational diabetes, caesarean section, and perinatal complications such as NICU admission, respiratory distress syndrome, low birth weight, and neonatal jaundice.

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References

1. Kvalvik LG, Wilcox AJ, Skjærven R, Østbye T, Harmon QE. Term complications and subsequent risk of preterm birth: registry-based study. BMJ. 2020;369:m1007. DOI: https://doi.org/10.1136/bmj.m1007

2. Reddy UM, Rice MM, Grobman WA, Bailit JL, Wapner RJ, Varner MW, et al. Serious maternal complications after early preterm delivery (24-33 weeks' gestation). Am J Obstet Gynecol. 2015;213(4):538.e1-538.e9.

3. Zivaljevic J, Jovandaric MZ, Babic S, Raus M. Complications of preterm birth—the importance of care for the outcome: a narrative review. Medicina (Kaunas). 2024;60(6):1014. DOI: https://doi.org/10.3390/medicina60061014

4. Chappell LC, Cluver CA, Tong S. Pre-eclampsia. Lancet. 2021;398(10297):341-354. DOI: https://doi.org/10.1016/S0140-6736(20)32335-7

5. Pittara T, Vyrides A, Lamnisos D, Giannakou K. Pre-eclampsia and long-term health outcomes for mother and infant: an umbrella review. BJOG. 2021;128(9):1421-1430. DOI: https://doi.org/10.1111/1471-0528.16683

6. von Dadelszen P, Syngelaki A, Akolekar R, Magee LA, Nicolaides KH. Preterm and term pre-eclampsia: relative burdens of maternal and perinatal complications. BJOG. 2023;130(5):524-530. DOI: https://doi.org/10.1111/1471-0528.17370

7. Cuenca-Gómez D, De Paco Matallana C, Rolle V, Mendoza M, Valiño N, Revello R, et al. Comparison of different methods of first-trimester screening for preterm pre-eclampsia: cohort study. Ultrasound Obstet Gynecol. 2024;64(1):57-64. DOI: https://doi.org/10.1002/uog.27622

8. Jamala F, Khan SJ, Ayub S, Tahir DN, Fasih A, Haider B, et al. Assessing barriers to successful breastfeeding among female postgraduate medical trainees: implications for supporting work-life balance. J Gandhara Med Dent Sci. 2025;12(4):33-38. DOI: https://doi.org/10.37762/jgmds.12-4.701

9. Riaz M, Askari S, Naseem R. Exploring maternal and neonatal outcomes in women with Type-1 diabetes: a study from Pakistan. Pak J Med Sci. 2024;40(7):1349-1354. DOI: https://doi.org/10.12669/pjms.40.7.9199

10. Ghaffar S, Channa S, Dars S, Khan S, Liaquat F, Shah H. Perinatal outcomes of high-risk pregnancies: experience of a tertiary care hospital. Pak J Health Sci. 2024;5(4):30-34. DOI: https://doi.org/10.54393/pjhs.v5i04.1385

11. Liu W, Liu Q, Liu W, Qiu C. Maternal risk factors and pregnancy complications associated with low birth weight neonates in preterm birth. J Obstet Gynaecol Res. 2021;47(9):3196-3202. DOI: https://doi.org/10.1111/jog.14830

12. Gonçalves JL, Fuertes M, Alves MJ, Antunes S, Almeida AR, Casimiro R, et al. Maternal pre- and perinatal experiences with their full-term, preterm, and very preterm newborns. BMC Pregnancy Childbirth. 2020;20(1):276. DOI: https://doi.org/10.1186/s12884-020-02934-8

13. Vekariya V, Vasani V. Maternal risk factors and perinatal outcomes in preterm birth: a retrospective analysis from a tertiary care hospital. Int J Curr Pharm Rev Res. 2025;17(3):1009-1012.

14. Begum K, Taranum UR, Waddedar P, Bhattacharjee S. Observing the maternal complications, fetal morbidity, and mortality of preterm birth. Sch Int J Obstet Gynecol. 2022;5(9):396-400. DOI: https://doi.org/10.36348/sijog.2022.v05i09.003

15. Dars S, Malik S, Samreen I, Kazi RA. Maternal morbidity and perinatal outcome in preterm premature rupture of membranes before 37 weeks of gestation. Pak J Med Sci. 2014;30(3):626-629. DOI: https://doi.org/10.12669/pjms.303.4853

16. Asma S, Muntaha ST, Hayat S, Hassan F. Comparison of fetal and maternal outcome in active vs conservative management of prelabor premature rupture of membranes (PPROM) at 34 to 37 weeks of gestation. J Islamabad Med Dent Coll. 2023;12(3):164-170. DOI: https://doi.org/10.35787/jimdc.v12i3.958

17. Akkuş F, Atcı AA, Doğru Ş, Ezveci H, Yaman FK, Demirtaş ŞY, et al. Comparison of maternal, fetal, and perinatal outcomes between adolescent and adult pregnancies: a retrospective case-control study. Perinatal Journal. 2024;32(1):70-76.

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Published

2025-05-31

How to Cite

1.
Khan F, Zahoor F, Khel SH, Gul H. Comparison of Maternal and Perinatal Complications in Preterm and Term Preeclampsia. Biol Clin Sci Res J [Internet]. 2025 May 31 [cited 2026 Aug. 8];6(5):460-3. Available from: https://bcsrj.com/ojs/index.php/bcsrj/article/view/2221

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